[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617249":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":59,"collaborators":26,"id":63,"slug":26,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Rhode Island Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ropivacaine","ACTIVE_COMPARATOR","30 ml of 0.25% ropivacaine; No dexmedetomidine",[13],"Drug: Ropivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Ropivacaine plus Dexmedetomidine","EXPERIMENTAL","30 ml of 0.25% ropivacaine; 1 mcg\u002Fkg of dexmedetomidine",[19,13],"Drug: Dexmedetomidine",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dexmedetomidine","Participants in the experimental arm receive a preoperative suprainguinal fascia iliaca block consisting of 30 mL of 0.25% ropivacaine combined with perineural dexmedetomidine at a dose of 1 mcg\u002Fkg.",[15],null,{"type":22,"name":9,"description":28,"armGroupLabels":29,"otherNames":26},"In the experimental arm, ropivacaine (30 mL of 0.25%) is administered with dexmedetomidine.\n\nIn the active comparator arm, ropivacaine (30 mL of 0.25%) is administered alone without any dexmedetomidine medication.",[9,15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Vendhan Ramanujam, M.D.","CONTACT","401-444-5172","vramanujam@brownhealth.org",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"The Miriam Hospital","RECRUITING","Providence","Rhode Island","02906","United States",{"type":45,"coordinates":46},"Point",[47,48],-71.41283,41.82399,{"lat":48,"lon":47},[51,55],{"name":52,"role":33,"phone":53,"phoneExt":26,"email":54},"Renee Dupre","401-793-4575","rdupre@brownhealth.org",{"name":56,"role":33,"phone":57,"phoneExt":26,"email":58},"Mark Kendall, M.D.","401-444-4722","mark.kendall@brownhealth.org",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Vendhan Ramanujam","Principal Investigator","100617249",false,"NCT07316166","Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine","Comparison of Suprainguinal Fascia Iliac Block With and Without Dexmedetomidine as an Adjunct to Ropivacaine for Postoperative Analgesia Following Hip Surgery: a Randomized, Double-blinded Study.","Inclusion Criteria:\n\n* Patients undergoing elective total hip arthroplasty\n* 18-80 years old\n* ASA 1-3 classifications\n\nExclusion Criteria:\n\n* ASA classification of 4 or greater\n* Infection at the site of nerve blockade\n* Coagulopathy\n* Known allergy to study medications\n* Chronic opioid consumption (\\>3 months)\n* Currently using lidocaine patches\n* Pre-existing neuropathy\n* A history of CVA\n* High grade atrioventricular block (cardiac conduction system impairment)\n* Organ dysfunction (cardiac failure, respiratory failure, end stage renal disease, hepatic dysfunction, hypoalbuminemia)\n* Morbid obesity (≥40 kg\u002Fm2)\n* Prior surgery in supra and\u002For infrainguinal region\n* Non-English-speaking participants","ALL","18 Years","80 Years",{"count":73,"type":74},120,"ESTIMATED","INTERVENTIONAL",[77],"PHASE4","The investigators are evaluating postoperative outcomes in patients undergoing hip replacement surgery performed with either spinal or general anesthesia, who also receive a suprainguinal fascia iliaca block using either perineural ropivacaine alone or ropivacaine combined with dexmedetomidine.",[80],"Postoperative Pain Management",[82,83],"Hip Surgery","Nerve block","2026-03-24",{"date":86,"type":87},"2026-03-25","ACTUAL",{"date":89,"type":87},"2026-01-20",{"date":91,"type":74},"2027-06",{"name":5,"class":6},1]