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A central randomized control group will be set up. The experimental and control groups will be populated at a 3:1 ratio. In addition to basic medication, the experimental group will be given Yangxinshi tablets (three tablets each time, three times a day); the control group will be given basic medication only. The treatment period is 24 weeks. The primary efficacy indicator is the 6-minute walking distance (6MWD).",[32,38],{"label":33,"type":34,"description":35,"interventionNames":36},"Experimental group","EXPERIMENTAL","basic medication + Yangxinshi tablet",[37],"Drug: Yangxinshi tablet",{"label":39,"type":6,"description":40,"interventionNames":41},"Control group","basic medication.",[42],"Other: Basic medication",[44,51],{"type":45,"name":46,"description":47,"armGroupLabels":48,"otherNames":49},"DRUG","Yangxinshi tablet","In addition to basic medication, the experimental group will be given Yangxinshi (three tablets each time, three times a day);The treatment period is 24 weeks.",[33],[50],"Yangxinshi",{"type":6,"name":52,"description":53,"armGroupLabels":54,"otherNames":21},"Basic medication","The control group will be given basic medication only. The treatment period is 24 weeks.",[39],[56],{"name":57,"affiliation":58,"role":59},"Yuan Haitao","Shandong Provincial Hospital","PRINCIPAL_INVESTIGATOR",[61],{"name":57,"role":62,"phone":63,"phoneExt":21,"email":64},"CONTACT","0531-68776356","doctoryuanht@126.com",[66,79,88,97,102,110,115,124,129,140,145,150,158,163,171,176,181,186,194,202,210,218,223,228,233,238,243,246,248,256,264,269],{"facility":67,"status":68,"city":69,"state":70,"zip":21,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":78,"contacts":21},"Shapingba District People's Hospital of Chongqing","NOT_YET_RECRUITING","Chongqing","Chongqing Municipality","China","CN",{"type":74,"coordinates":75},"Point",[76,77],106.55771,29.56026,{"lat":77,"lon":76},{"facility":80,"status":68,"city":81,"state":82,"zip":21,"country":71,"countryCode":72,"cosmosGeoPoint":83,"geoPoint":87,"contacts":21},"Zhengzhou Seventh People's 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Medicine","Yantai",{"type":74,"coordinates":273},[274,275],121.44081,37.47649,{"lat":275,"lon":274},{"type":278,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100529229",false,"NCT06171061","Yangxinshi Tablet Intervention for Exercise Capacity in Patients With Chronic Coronary Syndrome","Yangxinshi Tablet Intervention for Exercise Capacity in Patients With Chronic Coronary Syndrome: Prospective, Multicentre, Randomized, Open-label, Blinded-endpoint Clinical Trial","Inclusion Criteria:\n\n1. age 18-75 years;\n2. CCS patients in stable condition and clearly diagnosed by coronary artery imaging (at least one vessel stenosis ≥ 50%): stable angina, ischaemic cardiomyopathy, asymptomatic or stable symptoms, occult coronary heart disease, acute coronary syndrome (ACS), or \\>3 months after coronary revascularization;\n3. moderately to severely limited exercise tolerance: the maximum 6MWD is \\\u003C 450 m, or the metabolic equivalent (MET) as measured by treadmill cardiopulmonary exercise testing is \\\u003C 5 METs;\n4. voluntary participation and signing of informed consent.\n\nExclusion Criteria:\n\n1. absolute or relative contraindications for the treadmill cardiopulmonary exercise test or 6-minute walk test (6MWT);\n2. serious primary diseases, mental diseases, or malignant tumours that affect lifespan;\n3. pregnancy, intended or suspected pregnancy, miscarriage, breastfeeding, or delivery in the last 6 months;\n4. subjects not suitable for this study in the opinion of the researchers, such as subjects who are participating in other drug clinical trials or intervention studies.","ALL","18 Years","75 Years",{"count":289,"type":290},1200,"ESTIMATED","INTERVENTIONAL",[293],"PHASE4","This study is a prospective, multicentre, randomized, open-label, blinded-endpoint clinical trial to evaluate the efficacy and safety of Yangxinshi tablets in the treatment of patients with chronic coronary syndrome (CCS).",[296],"Chronic Coronary Syndrome",[50,296],"2024-04-16",{"date":300,"type":301},"2024-04-17","ACTUAL",{"date":303,"type":301},"2023-12-18",{"date":305,"type":290},"2026-12-31",{"name":5,"class":6},32]