Zynrelef Versus Adductor Canal Block
Trial statusNot yet recruiting
Trial phasePhase 4
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Miami
About this trial
To compare postoperative MME consumption 72 hours after TKA in patients receiving intraoperative periarticular HTX-011 (Zynrelef) instillation versus adductor canal block.
Eligibility criteria
Qualifiers
Patients > 18 years of age
Patients undergoing primary, unilateral total knee arthroplasty
Ability to provide informed consent
Disqualifiers
Individuals under the age of 18
Pregnant women
Prisoners
Adults unable to consent
Trial design
Treatments tested in this trial
- ZYNRELEF 400Mg-12Mg Extended-Release Solution
- Ultrasound-Guided Adductor Canal Block
- Ropivacaine 0.5% Injectable Solution
Treatment groups
120 Participants
are divided into 2 treatment groupsLocations
1University of Miami33125, MiamiFlorida, United States
Sponsors and collaborators
University of Miami
Lead sponsor
Source ClinicalTrials.gov