About this trial
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG). The study will compare two techniques for saphenous vein graft harvesting: the conventional technique and the no-touch technique. Participants will be randomly allocated into four groups: conventional harvesting with placebo, conventional harvesting with photobiomodulation, no-touch harvesting with placebo, and no-touch harvesting with photobiomodulation. The primary objective is to evaluate the effects of photobiomodulation on wound healing and postoperative complications related to the saphenous vein harvesting site. Secondary outcomes include clinical outcomes and functional capacity after surgery. The results may contribute to improving postoperative recovery and optimizing surgical strategies in patients undergoing myocardial revascularization.
Eligibility criteria
Qualifiers
Patients diagnosed with coronary artery disease scheduled to undergo elective coronary artery bypass grafting (CABG)
Use of the saphenous vein as a graft for myocardial revascularization
Ability to understand the study procedures and provide written informed consent
Disqualifiers
Emergency coronary artery bypass surgery
Previous surgery in the lower limb that prevents saphenous vein harvesting
Active infection at the surgical site or lower limb
Severe peripheral arterial disease in the lower limbs
Trial design
Treatments tested in this trial
- Photobiomodulation Therapy
- Placebo Laser
- Conventional Saphenous Vein Harvesting
- No-Touch Saphenous Vein Harvesting
Treatment groups
Locations
1Sponsors and collaborators
Federal University of São Paulo
Lead sponsor