[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100400646":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":34,"responsibleParty":49,"collaborators":18,"id":52,"slug":18,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":18,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":18,"overallStatus":36,"whyStopped":18,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Stress Reduction","EXPERIMENTAL","8 week stress reduction course",[13],"Behavioral: Stress Reduction",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","No intervention",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","The stress reduction program is a multimodal mind-body resiliency program that incorporates 3 core components into each session:\n\n* Elicitation of the Relaxation Response (RR) through mind-body techniques;\n* Discussion about stress awareness to learn how to identify personal stressors and experiences of stress; and\n* Coping strategies and adaptive perspective-taking to promote positive well-being.",[9],[25],{"name":26,"affiliation":27,"role":28},"Ahmed Tawakol, MD","MGH","PRINCIPAL_INVESTIGATOR",[30],{"name":26,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","6177243699","atawakol@mgh.harvard.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Boston","Massachusetts","02114","United States",{"type":42,"coordinates":43},"Point",[44,45],-71.05977,42.35843,{"lat":45,"lon":44},[48],{"name":26,"role":31,"phone":32,"phoneExt":18,"email":33},{"type":28,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Ahmed Tawakol","Director, Nuclear Cardiology","100400646",false,"NCT04496947","Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study","Inclusion Criteria:\n\n* • Aged between 30-65 years\n\n  * Identifies as having increased levels of stress and\u002For has a Perceived Stress Scale (PSS) score \\>5 at baseline, and is interested in participating\n\nExclusion Criteria:\n\n* Perceived Stress Scale (PSS) score \\\u003C6",true,"ALL","30 Years","65 Years",{"count":62,"type":63},30,"ESTIMATED","INTERVENTIONAL",[66],"NA","The plot study aims to evaluate the effect of 8 weeks of stress reducing intervention on atherosclerotic plaque inflammation in adults, as quantified by positron emission tomography (PET) with fluorine-2-deoxy-D-glucose (FDG) in individuals with increased psychosocial stress.",[69,70,71],"Atherosclerosis","Stress","Inflammation","2026-05-31",{"date":74,"type":75},"2026-06-03","ACTUAL",{"date":77,"type":75},"2018-09-01",{"date":79,"type":63},"2027-12-31",{"name":5,"class":6},1]