[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565488":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":27,"responsibleParty":45,"collaborators":48,"id":52,"slug":10,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":66,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University Hospital Erlangen","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Women with PCOS",null,"Women in the age range of 15-25 years fulfilling the PCOS criteria defined by the International Evidence-based Guideline",{"label":13,"type":10,"description":14,"interventionNames":10},"Women without PCOS (controls)","Women in the age range of 15-25 years who are negative for the diagnostic criteria of PCOS according to the International Evidence based guideline",[16],{"name":17,"affiliation":5,"role":18},"Ralf Dittrich, Prof.","PRINCIPAL_INVESTIGATOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Laura Lotz, Dr. med.","CONTACT","+49 9131 85 44023","laura.lotz@uk-erlangen.de",{"name":17,"role":22,"phone":10,"phoneExt":10,"email":26},"ralf.dittrich@uk-erlangen.de",[28],{"facility":29,"status":30,"city":31,"state":10,"zip":32,"country":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Department of Obstetrics and Gynecology, University Erlangen Hospital, Friedrich Alexander University of Erlangen-Nuremberg, Erlangen, Germany","RECRUITING","Erlangen","91054","Germany",{"type":35,"coordinates":36},"Point",[37,38],11.00783,49.59099,{"lat":38,"lon":37},[41,43],{"name":42,"role":22,"phone":23,"phoneExt":10,"email":24},"Laura Lotz, Dr",{"name":44,"role":22,"phone":10,"phoneExt":10,"email":26},"Ralf Dittrich, Prof",{"type":18,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Laura Lotz","PD Dr. med.",[49],{"name":50,"class":51},"Roche Diagnostics International AG","INDUSTRY","100565488",false,"NCT06642831","Polycystic Ovarian Syndrome (PCOS) Biomarker Evaluation Study","Polycystic Ovarian Syndrome (PCOS) in Human Adolescent and Young Adult Females - Biomarker Evaluation Study (PHOEBE)","PHOEBE","Inclusion Criteria:\n\n* Female subjects age 15-25 years\n* Signed written informed consent\n\nExclusion Criteria:\n\n* Less than 1 years from onset of menarche\n* Use of hormonal contraceptives\n* Documented ongoing pregnancy\n* Major ovarian abnormalities, including subject with only one ovary, cysts and solid masses \\> 2 cm as detected by transvaginal ultrasound\n* Malignancy ( documented malignancy, documentation of current radiation therapy or chemotherapy in medical record)",true,"FEMALE","15 Years","25 Years",{"count":64,"type":65},380,"ESTIMATED","1 Year","OBSERVATIONAL","The purpose of the study is to validate recently identified biomarkers for the identification of PCOS in adolecent and young adult women.",[70],"Polycystic Ovarian Syndrome (PCOS)",[72,73,74],"PCOS","biomarker","adolescents","2024-10-14",{"date":77,"type":78},"2024-10-15","ACTUAL",{"date":80,"type":78},"2023-01-31",{"date":82,"type":65},"2027-03",{"name":5,"class":6},1]