[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100437961":3},{"organization":4,"outcomesModule":7,"designInfo":42,"detailedDescription":45,"studyPopulation":46,"armGroups":41,"interventions":41,"overallOfficials":47,"centralContacts":51,"locations":62,"responsibleParty":81,"collaborators":41,"id":83,"slug":41,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":84,"sex":90,"minAge":91,"maxAge":41,"enrollmentInfo":92,"targetDuration":41,"studyType":95,"phases":41,"briefSummary":96,"conditions":97,"keywords":41,"overallStatus":65,"whyStopped":41,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Portsmouth Hospitals NHS Trust","OTHER_GOV",{"primaryOutcomes":8,"secondaryOutcomes":23,"otherOutcomes":41},[9,13,15,18,19,22],{"measure":10,"description":11,"timeFrame":12},"In-hospital death","Death during hospital admission","At 24 hours after an observation assessment or physiological measurement",{"measure":10,"description":11,"timeFrame":14},"30 days after admission",{"measure":16,"description":17,"timeFrame":12},"Unanticipated ICU admission","Unanticipated ICU admission during hospital stay",{"measure":16,"description":17,"timeFrame":14},{"measure":20,"description":21,"timeFrame":12},"Cardiac arrest","Cardiac arrest during hospital stay",{"measure":20,"description":21,"timeFrame":14},[24,28,30,34,35,37,39],{"measure":25,"description":26,"timeFrame":27},"Diagnosis of Corona Virus Disease (COVID) infection","Diagnosis of COVID-19","48 hours after presentation",{"measure":25,"description":26,"timeFrame":29},"At 48 hours after an observation assessment or physiological measurement",{"measure":31,"description":32,"timeFrame":33},"Detection of Acute Organ Dysfunction","Detection of acute organ dysfunction as measured by components of the Sequential Organ Failure Assessment (SOFA) Score","24 hours after presentation",{"measure":31,"description":32,"timeFrame":27},{"measure":31,"description":32,"timeFrame":36},"72 hours after presentation",{"measure":31,"description":32,"timeFrame":38},"1 week after presentation",{"measure":31,"description":32,"timeFrame":40},"30 days after presentation",null,{"allocation":41,"interventionModel":41,"interventionModelDescription":41,"primaryPurpose":41,"observationalModel":43,"timePerspective":44,"maskingInfo":41},"COHORT","RETROSPECTIVE","The aims and objectives of this database of depersonalised routinely collected hospital patient data are to:\n\n* Conduct epidemiological and observational studies of acute hospital care.\n* Develop and use algorithms and risk models to identify the deteriorating \u002F sick adult so that interventions and enhanced care can be provided in a timelier manner with consequent resource and outcome improvements. This covers both the deteriorating inpatient at risk of adverse outcomes and people in the local community at risk of hospitalisation or in need of other health services.\n* Retrospectively evaluate interventions e.g. impact of system-wide clinical pathway introduction\n* Conduct simulations of clinical pathways","The research database will hold data on adults who are treated by Portsmouth Hospitals University National Health Service Trust (PHU), either as an outpatient, Accident and Emergency (A\\&E) attender, day case or inpatient or have investigations carried out by PHU services Adult patients are defined by the National Health Service (NHS) as individuals over 16 years old. Data on service contacts and use will only be included where the patient was more than 16 years old at that time. None of the data included in the Clinical Outcomes analyses are collected specifically for the purposes of research. All datasets are routinely collected clinical datasets, collected for clinical use and clinical audit.",[48],{"name":49,"affiliation":5,"role":50},"Paul E Schmidt, MRCP","PRINCIPAL_INVESTIGATOR",[52,58],{"name":53,"role":54,"phone":55,"phoneExt":56,"email":57},"Paul Meredith, PhD","CONTACT","023 92286000","3774","paul.meredith@porthosp.nhs.uk",{"name":59,"role":54,"phone":55,"phoneExt":60,"email":61},"Alice Mortlock, PhD","4042","alice.mortlock@porthosp.nhs.uk",[63],{"facility":64,"status":65,"city":66,"state":67,"zip":68,"country":69,"countryCode":70,"cosmosGeoPoint":71,"geoPoint":76,"contacts":77},"Queen Alexandra Hospital","RECRUITING","Portsmouth","Hampshire","PO6 3LY","United Kingdom","UK",{"type":72,"coordinates":73},"Point",[74,75],-1.09125,50.79899,{"lat":75,"lon":74},[78,80],{"name":79,"role":54,"phone":41,"phoneExt":41,"email":41},"Paul E Schmidt",{"name":79,"role":50,"phone":41,"phoneExt":41,"email":41},{"type":82,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR","100437961",false,"NCT04983082","Portsmouth CORE-D Routine Care Data Repository","Portsmouth Clinical Outcomes REsearch Database (CORE-D)- a Research Database of Routine Electronically Recorded Patient Data to Model Adverse Clinical Outcomes and Healthcare Resource Usage","CORE-D","Inclusion Criteria:\n\n* Adult presenting at the acute hospital or receiving services from the hospital\n\nExclusion Criteria:\n\n* Adults who have registered an opt out of research with National Health Service (NHS) Digital\n* Adults who have contacted the hospital to ask that their records are not to be included in this study","ALL","16 Years",{"count":93,"type":94},750000,"ESTIMATED","OBSERVATIONAL","An integrated database of depersonalised routine hospital patient data consisting of demographic and disease attributes, physiological or laboratory measurements, care contacts and interventions along with associated clinical outcomes. The database is an essential resource for the development and testing of risk models and classification systems, modified as necessary for patient subgroups, which can then be introduced into clinical care to improve patient outcomes. It can also be used for large scale simulations to evaluate interventions.",[98],"Adult Hospital Patients at Risk of Adverse Outcomes","2026-06-24",{"date":101,"type":102},"2026-06-29","ACTUAL",{"date":104,"type":102},"2021-08-19",{"date":106,"type":94},"2031-04",{"name":5,"class":6},1]