Persistent residual limb pain is common after traumatic amputation and significantly impairs rehabilitation and prosthetic use. Postoperative stump infection may contribute to peripheral nerve sensitization, scar fibrosis, and long-term pain persistence. This prospective cohort study aims to determine whether early post-amputation stump infection independently predicts persistent clinically significant residual limb pain at 3 and 6 months after surgery.
Traumatic upper or lower limb amputation
Enrollment within 4 weeks after surgery
Ability to provide informed consent
Pre-existing chronic pain in the affected limb
Severe cognitive impairment
Terminal illness limiting follow-up
Refusal or inability to complete follow-up assessments
Ukrainian Society of Regional Anesthesia and Pain Therapy
Lead sponsor