[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100310210":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":23,"centralContacts":28,"locations":34,"responsibleParty":319,"collaborators":10,"id":321,"slug":10,"hasResults":322,"nctId":323,"briefTitle":324,"officialTitle":325,"acronym":10,"eligibilityCriteria":326,"healthyVolunteers":322,"sex":327,"minAge":328,"maxAge":10,"enrollmentInfo":329,"targetDuration":332,"studyType":333,"phases":10,"briefSummary":334,"conditions":335,"keywords":337,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":340,"lastUpdatePostDateStruct":341,"startDateStruct":344,"completionDateStruct":346,"leadSponsor":348,"locationsCount":349},{"fullName":5,"class":6},"Uptake Medical Technology, Inc.","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"BTVA treated patients",null,"Patients with heterogeneous upper lobe emphysema undergoing Bronchoscopic Thermal Vapor Ablation treatment",[13],"Device: Bronchoscopic Thermal Vapor Ablation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Bronchoscopic Thermal Vapor Ablation","Bronchoscopic vapor delivery to airway segment(s) targeted for treatment",[9],[21,22],"BTVA","InterVapor",[24],{"name":25,"affiliation":26,"role":27},"Felix Herth, MD, PhD","Heidelberg University","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Jennifer Idris","CONTACT","+1-408-391-0098","jidris@broncus.com",[35,53,68,83,95,110,125,140,157,172,187,200,215,230,242,255,270,285,295,307],{"facility":36,"status":37,"city":38,"state":10,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Krankenhaus Nord - Klinik Floridsdorf","RECRUITING","Vienna","1210","Austria",{"type":42,"coordinates":43},"Point",[44,45],16.37208,48.20849,{"lat":45,"lon":44},[48,51],{"name":49,"role":31,"phone":10,"phoneExt":10,"email":50},"Welz Kelly","kelly.welz@extern.gesundheitsverbund.at",{"name":52,"role":27,"phone":10,"phoneExt":10,"email":10},"Arschang Valipour, MD",{"facility":54,"status":37,"city":55,"state":10,"zip":56,"country":57,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Sozialstiftung Bamberg, Klinikum am Bruderwald","Bamberg","96049","Germany",{"type":42,"coordinates":59},[60,61],10.90067,49.89873,{"lat":61,"lon":60},[64,66],{"name":65,"role":31,"phone":10,"phoneExt":10,"email":10},"Beate Klaus",{"name":67,"role":27,"phone":10,"phoneExt":10,"email":10},"Wolfgang Hohenforst-Schmidt, MD",{"facility":69,"status":37,"city":70,"state":10,"zip":71,"country":57,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"DRK Kliniken Berlin \u002F Mitte","Berlin","13359",{"type":42,"coordinates":73},[74,75],13.41053,52.52437,{"lat":75,"lon":74},[78,81],{"name":79,"role":31,"phone":10,"phoneExt":10,"email":80},"Jeanette Natschke","j.natschke@drk-kliniken-berlin.de",{"name":82,"role":27,"phone":10,"phoneExt":10,"email":10},"Bernd Schmidt, MD",{"facility":84,"status":37,"city":70,"state":10,"zip":85,"country":57,"cosmosGeoPoint":86,"geoPoint":88,"contacts":89},"FORSCHUNGSINSTITUT Havelhöhe gGmbH","14089",{"type":42,"coordinates":87},[74,75],{"lat":75,"lon":74},[90,93],{"name":91,"role":31,"phone":10,"phoneExt":10,"email":92},"Claudia Leichnitz","Claudia.leichnitz@havelhohe.de",{"name":94,"role":27,"phone":10,"phoneExt":10,"email":10},"Christian Grah, MD",{"facility":96,"status":37,"city":97,"state":10,"zip":98,"country":57,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Ruhrlandklinik - Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH","Essen","45147",{"type":42,"coordinates":100},[101,102],7.01228,51.45657,{"lat":102,"lon":101},[105,108],{"name":106,"role":31,"phone":10,"phoneExt":10,"email":107},"Birte Schwarz","birte.schwarz@uk-essen.de",{"name":109,"role":27,"phone":10,"phoneExt":10,"email":10},"Kaid Darwiche, MD",{"facility":111,"status":37,"city":112,"state":10,"zip":113,"country":57,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Asklepios Fachkliniken München-Gauting","Gauting","82131",{"type":42,"coordinates":115},[116,117],11.37703,48.06919,{"lat":117,"lon":116},[120,123],{"name":121,"role":31,"phone":10,"phoneExt":10,"email":122},"Rosalie Untsch","ro.untsch@asklepios.com",{"name":124,"role":27,"phone":10,"phoneExt":10,"email":10},"Wolfgang Gesierich, MD",{"facility":126,"status":37,"city":127,"state":10,"zip":128,"country":57,"cosmosGeoPoint":129,"geoPoint":133,"contacts":134},"Martin-Luther-Universität Halle-Wittenberg (Saale)","Halle","06120",{"type":42,"coordinates":130},[131,132],11.97947,51.48158,{"lat":132,"lon":131},[135,138],{"name":136,"role":31,"phone":10,"phoneExt":10,"email":137},"Susanne Behl","susanne.behl@uk-halle.de",{"name":139,"role":27,"phone":10,"phoneExt":10,"email":10},"Stephan Eisenmann, MD",{"facility":141,"status":37,"city":142,"state":10,"zip":143,"country":57,"cosmosGeoPoint":144,"geoPoint":148,"contacts":149},"Thoraxklinik Heidelberg","Heidelberg","69126",{"type":42,"coordinates":145},[146,147],8.69079,49.40768,{"lat":147,"lon":146},[150,153,154],{"name":151,"role":31,"phone":10,"phoneExt":10,"email":152},"Michaela Korthoeber","michaela.korthoeber@med.uni-heidelberg.de",{"name":25,"role":27,"phone":10,"phoneExt":10,"email":10},{"name":155,"role":156,"phone":10,"phoneExt":10,"email":10},"Ralf Eberhardt, MD","SUB_INVESTIGATOR",{"facility":158,"status":37,"city":159,"state":10,"zip":160,"country":57,"cosmosGeoPoint":161,"geoPoint":165,"contacts":166},"Lungenklinik Hemer","Hemer","58675",{"type":42,"coordinates":162},[163,164],7.77019,51.38707,{"lat":164,"lon":163},[167,170],{"name":168,"role":31,"phone":10,"phoneExt":10,"email":169},"Anja Schmidt","Anja.Schmidt@lkhemer.de",{"name":171,"role":27,"phone":10,"phoneExt":10,"email":10},"Franz Stanzel, MD",{"facility":173,"status":37,"city":174,"state":10,"zip":175,"country":57,"cosmosGeoPoint":176,"geoPoint":180,"contacts":181},"Lungenfachklinik Immenhausen","Immenhausen","34376",{"type":42,"coordinates":177},[178,179],9.48017,51.42763,{"lat":179,"lon":178},[182,185],{"name":183,"role":31,"phone":10,"phoneExt":10,"email":184},"Katrin Schwedler","k.schwedler@lungenfachklinik-immenhausen.de",{"name":186,"role":27,"phone":10,"phoneExt":10,"email":10},"Peter Hammerl, MD",{"facility":188,"status":189,"city":190,"state":10,"zip":191,"country":57,"cosmosGeoPoint":192,"geoPoint":196,"contacts":197},"Krankenhaus Martha-Maria München","NOT_YET_RECRUITING","München","81479",{"type":42,"coordinates":193},[194,195],13.31243,51.60698,{"lat":195,"lon":194},[198],{"name":199,"role":27,"phone":10,"phoneExt":10,"email":10},"Andreas Fertl, MD",{"facility":201,"status":37,"city":202,"state":10,"zip":203,"country":57,"cosmosGeoPoint":204,"geoPoint":208,"contacts":209},"Klinikum Nürnberg Nord","Nuremberg","90419",{"type":42,"coordinates":205},[206,207],11.07752,49.45421,{"lat":207,"lon":206},[210,213],{"name":211,"role":31,"phone":10,"phoneExt":10,"email":212},"Tanja Goetz","tanja.goetz@klinikum-nuernberg.de",{"name":214,"role":27,"phone":10,"phoneExt":10,"email":10},"Joachim Ficker, MD",{"facility":216,"status":37,"city":217,"state":10,"zip":218,"country":57,"cosmosGeoPoint":219,"geoPoint":223,"contacts":224},"Krankenhaus vom Roten Kreuz Bad Cannstatt GmbH","Stuttgart","70372",{"type":42,"coordinates":220},[221,222],9.17702,48.78232,{"lat":222,"lon":221},[225,228],{"name":226,"role":31,"phone":10,"phoneExt":10,"email":227},"Ute Höß","ute.hoess@sana.de",{"name":229,"role":27,"phone":10,"phoneExt":10,"email":10},"Martin Hetzel, MD",{"facility":231,"status":37,"city":217,"state":10,"zip":232,"country":57,"cosmosGeoPoint":233,"geoPoint":235,"contacts":236},"Klinik Schillerhöhe","70376",{"type":42,"coordinates":234},[221,222],{"lat":222,"lon":221},[237,240],{"name":238,"role":31,"phone":10,"phoneExt":10,"email":239},"Nina Lutz","nina.lutz@rbk.de",{"name":241,"role":27,"phone":10,"phoneExt":10,"email":10},"Claus Neurohr, MD",{"facility":243,"status":37,"city":244,"state":10,"zip":245,"country":246,"cosmosGeoPoint":247,"geoPoint":251,"contacts":252},"Kantonsspital Aarau AG","Aarau","5001","Switzerland",{"type":42,"coordinates":248},[249,250],8.04422,47.39254,{"lat":250,"lon":249},[253],{"name":254,"role":27,"phone":10,"phoneExt":10,"email":10},"Sarosh Irani, MD",{"facility":256,"status":189,"city":257,"state":10,"zip":258,"country":246,"cosmosGeoPoint":259,"geoPoint":263,"contacts":264},"University Hospital Basel","Basel","4031",{"type":42,"coordinates":260},[261,262],7.57327,47.55839,{"lat":262,"lon":261},[265,268],{"name":266,"role":31,"phone":10,"phoneExt":10,"email":267},"Sandra Kunze","Sandra.Kunze@usb.ch",{"name":269,"role":27,"phone":10,"phoneExt":10,"email":10},"Michael Tamm, MD",{"facility":271,"status":37,"city":272,"state":10,"zip":273,"country":246,"cosmosGeoPoint":274,"geoPoint":278,"contacts":279},"Lungen-und Schlafzentrum am Lindenhofspital AG, Bern","Bern","3012",{"type":42,"coordinates":275},[276,277],7.44744,46.94809,{"lat":277,"lon":276},[280,283],{"name":281,"role":31,"phone":10,"phoneExt":10,"email":282},"Tina Lauper","tina.lauper@pneumo-lindenhof.ch",{"name":284,"role":27,"phone":10,"phoneExt":10,"email":10},"Kaspar Remund, MD",{"facility":286,"status":287,"city":288,"state":10,"zip":289,"country":246,"cosmosGeoPoint":290,"geoPoint":294,"contacts":10},"Kantonsspital St.Gallen","WITHDRAWN","Sankt Gallen","9000",{"type":42,"coordinates":291},[292,293],9.37477,47.42391,{"lat":293,"lon":292},{"facility":296,"status":37,"city":297,"state":10,"zip":298,"country":246,"cosmosGeoPoint":299,"geoPoint":303,"contacts":304},"LungenZentrum Hirslanden","Zurich","8032",{"type":42,"coordinates":300},[301,302],8.55,47.36667,{"lat":302,"lon":301},[305],{"name":306,"role":27,"phone":10,"phoneExt":10,"email":10},"Karl Klingler, MD",{"facility":308,"status":37,"city":297,"state":10,"zip":309,"country":246,"cosmosGeoPoint":310,"geoPoint":312,"contacts":313},"Universitäts Spital Zürich","8091",{"type":42,"coordinates":311},[301,302],{"lat":302,"lon":301},[314,317],{"name":315,"role":31,"phone":10,"phoneExt":10,"email":316},"Christa Bodmer","Christa.Bodmer@usz.ch",{"name":318,"role":27,"phone":10,"phoneExt":10,"email":10},"Daniel Franzen, MD",{"type":320,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100310210",false,"NCT03318406","Post-Market BTVA Registry","Post-Market Registry for Patients With Emphysema Treated With BTVA","Inclusion Criteria:\n\n1. Patients will have heterogeneous emphysema, as evidenced by high-resolution computed tomography (HRCT) demonstrating a heterogeneity index \\> or equal to 1.2 in at least one segment to be treated\n2. Patients must be \\> or equal to 18 years of age\n3. Patients are required to provide informed consent prior to inclusion in the Registry\n\nExclusion Criteria:\n\n1. FEV1 \\\u003C 20% predicted\n2. DLCO \\\u003C 20% predicted\n3. Inability to walk \\> 140 meters in 6 minutes (6MWD) following optimized medical management\n4. Unstable COPD (any of the following):\n\n   1. \\> 3 COPD related hospitalizations requiring antibiotics in past 12 months\n   2. COPD related hospitalization in past 3 months\n   3. daily use of systemic steroids, i.e. \\> 5 mg prednisolone\n5. Concomitant illnesses or medications that would pose a significant increased risk for complications following treatment with InterVapor. Examples of particular relevance include: immune system disorders, immunosuppressant medications of clinical relevance, bleeding disorders and unstable cardiovascular conditions, history of asthma or alpha-1 antitrypsin deficiency\n6. Newly prescribed morphine derivatives within the last 4 weeks\n7. Pregnant or breastfeeding\n8. Highly diseased lower lobes (tissue to air ratio of \\\u003C11%)\n9. Bacterial infection or symptoms indicative of active infection (i.e., fever, elevated white blood cell count)\n10. Presence of single large bulla (defined as \\> 1\u002F3 volume of lobe) or a paraseptal distribution of emphysema in the treated lobe\n11. Recent respiratory infections or COPD exacerbation in preceding 6 weeks -","ALL","18 Years",{"count":330,"type":331},300,"ESTIMATED","5 Years","OBSERVATIONAL","Bronchoscopic thermal vapor ablation using Uptake Medical Technology Inc.'s InterVapor System is indicated for treatment of patients with heterogeneous upper lobe emphysema. This study is a retrospective and prospective, observational, multi-center, post-market registry of patients prescribed InterVapor. The primary objective of the Registry is to describe the long-term impact of InterVapor treatment on patient quality of life (QOL) in a real-world setting. After InterVapor treatment, patients will be followed for 5 years as per the standard of care and safety and efficacy data (quality of life, pulmonary function, exercise capacity) collected as part of the registry.",[336],"Emphysema or COPD",[338,339,22,21],"registry","vapor ablation","2025-01-25",{"date":342,"type":343},"2025-01-28","ACTUAL",{"date":345,"type":343},"2018-03-22",{"date":347,"type":331},"2030-12-01",{"name":5,"class":6},20]