[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100489440":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":26,"responsibleParty":40,"collaborators":10,"id":44,"slug":10,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":10,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Insel Gruppe AG, University Hospital Bern","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Stroke patients",null,"Adults with first-ever anterior circulation stroke",[13],{"name":14,"affiliation":15,"role":16},"Roza M. Umarova, PD Dr.","Department of Neurology, Inselspital, University Hospital Bern, University of Bern","PRINCIPAL_INVESTIGATOR",[18,22],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},"CONTACT","+41316327000","roza.umarova@insel.ch",{"name":23,"role":19,"phone":24,"phoneExt":10,"email":25},"Laura Gallucci, MSc","+41316641506","laura.gallucci@extern.insel.ch",[27],{"facility":15,"status":28,"city":29,"state":10,"zip":30,"country":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Bern","3010","Switzerland",{"type":33,"coordinates":34},"Point",[35,36],7.44744,46.94809,{"lat":36,"lon":35},[39],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Roza Umarova","PD Dr., Principal Investigator, Head of out-patient clinic of cognitive neurology","100489440",false,"NCT05653141","Post-stroke Cognitive Impairment","Prediction of Post-stroke Cognitive Decline and Dementia: Impact of Cognitive Reserve and Post-stroke Life Style","CogStroke","Inclusion Criteria:\n\n* Age ≥18 years old\n* First-ever anterior circulation ischemic stroke confirmed by routine MRI\n* Time of enrollment: ≤ 10 days from stroke onset.\n\nExclusion Criteria:\n\n* Previous stroke anamnestic or based on clinical imaging\n* Additional stroke in posterior circulation\n* Conditions that preclude the cognitive testing (e.g. delirium, intubation, reduced vigilance\n* Neurological or psychiatric conditions that preclude the data interpretation (e.g. pre-stroke dementia, schizophrenia, brain tumor, regular intake of benzodiazepine, depression)\n* MRI contraindication\n* Native language other than German, French or Italian","ALL","18 Years",{"count":54,"type":55},600,"ESTIMATED","OBSERVATIONAL","Present study aims to track the post-stroke cognitive trajectories and to investigate its inter-individual variability.",[59,60],"First-ever Ischemic Stroke","Cognitive Performance",[62,63],"Ischemic stroke","Cognitive reserve","2026-04-29",{"date":66,"type":67},"2026-05-06","ACTUAL",{"date":69,"type":67},"2020-12-17",{"date":71,"type":55},"2029-10-31",{"name":42,"class":6},1]