[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616775":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":29,"responsibleParty":111,"collaborators":114,"id":124,"slug":10,"hasResults":125,"nctId":126,"briefTitle":127,"officialTitle":127,"acronym":10,"eligibilityCriteria":128,"healthyVolunteers":125,"sex":129,"minAge":130,"maxAge":131,"enrollmentInfo":132,"targetDuration":10,"studyType":135,"phases":10,"briefSummary":136,"conditions":137,"keywords":143,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":154},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Low Pa02 Group",null,"Patients were defined as belonging to the Low PaO₂ group if they exhibited at least one recorded instance of PaO₂ \\\u003C80 mmHg within the first postoperative week.",{"label":13,"type":10,"description":14,"interventionNames":10},"Normal PaO2 Group","Patients maintained a PaO₂ ≥80 mmHg throughout the first postoperative week.",[16],{"name":17,"affiliation":18,"role":19},"Hong Yang, M.D.","Department of Thoracic Surgery, Sun Yat-sen University Cancer Center","PRINCIPAL_INVESTIGATOR",[21,25],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","8613560405144","yanghong@sysucc.org.cn",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Yizhang Chen, M.D. candidate","8613533718832","chenyizhang@sysucc.org.cn",[30,44,57,71,85,99],{"facility":18,"status":31,"city":32,"state":33,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Guangzhou","Guangdong","510060","China",{"type":37,"coordinates":38},"Point",[39,40],113.25,23.11667,{"lat":40,"lon":39},[43],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},{"facility":45,"status":31,"city":46,"state":33,"zip":10,"country":35,"cosmosGeoPoint":47,"geoPoint":51,"contacts":52},"Cancer Hospital of Shantou University Medical College","Shantou",{"type":37,"coordinates":48},[49,50],116.67876,23.35489,{"lat":50,"lon":49},[53],{"name":54,"role":22,"phone":55,"phoneExt":10,"email":56},"Shaobin Li, MD","0754 8855 5844","chensb535176@hotmail.com",{"facility":58,"status":31,"city":59,"state":60,"zip":10,"country":35,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital","Shijiazhuang","Hebei",{"type":37,"coordinates":62},[63,64],114.47861,38.04139,{"lat":64,"lon":63},[67],{"name":68,"role":22,"phone":69,"phoneExt":10,"email":70},"Xinjian Xu, MD","0311-86095588","syxuxinjian0799@hebmu.edu.cn",{"facility":72,"status":31,"city":73,"state":74,"zip":10,"country":35,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Shanghai Chest Hospital","Shanghai","Shanghai Municipality",{"type":37,"coordinates":76},[77,78],121.45806,31.22222,{"lat":78,"lon":77},[81],{"name":82,"role":22,"phone":83,"phoneExt":10,"email":84},"Zhigang Li, MD","021-22200000","zhigang.li@shsmu.edu.cn",{"facility":86,"status":31,"city":87,"state":88,"zip":10,"country":35,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"Sichuan Cancer Hospital","Chengdu","Sichuan",{"type":37,"coordinates":90},[91,92],104.06667,30.66667,{"lat":92,"lon":91},[95],{"name":96,"role":22,"phone":97,"phoneExt":10,"email":98},"Xuefeng Leng, MD","028 8542 0305","leng724@163.com",{"facility":100,"status":31,"city":101,"state":88,"zip":10,"country":35,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"0817-2598459","Nanchong",{"type":37,"coordinates":103},[104,105],106.08473,30.79508,{"lat":105,"lon":104},[108],{"name":109,"role":22,"phone":10,"phoneExt":10,"email":110},"Hao Yang, MD","501912904@qq.com",{"type":19,"investigatorFullName":112,"investigatorTitle":113,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Yang Hong","Professor",[115,117,119,121,123],{"name":116,"class":6},"Sichuan Cancer Hospital and Research Institute",{"name":118,"class":6},"Affiliated Hospital of North Sichuan Medical College",{"name":120,"class":6},"Hebei Medical University Fourth Hospital",{"name":122,"class":6},"Affiliated Cancer Hospital of Shantou University Medical College",{"name":72,"class":6},"100616775",false,"NCT07309991","Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy","Inclusion Criteria:\n\n* Patients diagnosed with esophageal carcinoma or benign esophageal tumors\n* Patients requiring surgical resection of the lesion with subsequent esophageal reconstruction\n* Patients must have had at least one postoperative arterial blood gas analysis\n* Patients must have routinely undergone at least one of the following for postoperative evaluation of the anastomosis: endoscopy, CT scan, or esophagram\n\nExclusion Criteria:\n\n* Patients who did not require esophageal reconstruction\n* Patients undergoing esophageal replacement with colon\n* Patients with incomplete data","ALL","18 Years","80 Years",{"count":133,"type":134},2500,"ESTIMATED","OBSERVATIONAL","This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)\\\u003C80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy. The investigators conducted a retrospective analysis of cases from their center over the past five years, stratifying patients into Low Pa0₂ Group and Normal Pa0₂ Group based on postoperative oxygen levels and comparing the incidence of anastomotic leakage between the groups. The goal is to establish whether hypoxia is a causative risk factor and whether correcting it can reduce the risk of anastomotic leakage.",[138,139,140,141,142],"Esophageal Carcinoma","Esophageal Adenocarcinoma","Esophagectomy","PaO2","Esophageal Anastomotic Leakeage",[144],"Effect of Postoperative PaO₂ on Anastomotic Leakage Following Esophagectomy","2026-06-13",{"date":147,"type":148},"2026-06-16","ACTUAL",{"date":150,"type":148},"2021-01-01",{"date":152,"type":134},"2026-12-01",{"name":5,"class":6},6]