[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100507529":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":61,"collaborators":26,"id":63,"slug":26,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":26,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Tianjin Medical University Cancer Institute and Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"prepectoral breast reconstruction with Mesh","ACTIVE_COMPARATOR","Immediate prepectoral breast reconstruction with Mesh",[13,14],"Procedure: prepectoral breast reconstruction","Procedure: Tiloop Mesh implantation",{"label":16,"type":17,"description":18,"interventionNames":19},"prepectoral breast reconstruction without Mesh","EXPERIMENTAL","Immediate prepectoral breast reconstruction without Mesh",[13],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","prepectoral breast reconstruction","Patients receive immediate prepectoral breast reconstruction",[9,16],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Tiloop Mesh implantation","Patients receive immediate prepectoral breast reconstruction with Tiloop Mesh",[9],[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Jian Yin","CONTACT","+86-22-23340123","1171","yinjian@tjmuch.com",{"name":39,"role":34,"phone":35,"phoneExt":36,"email":40},"Chunyong Han","hancy_007@126.com",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Tianjin","Tianjin Municipality","300060","China",{"type":49,"coordinates":50},"Point",[51,52],117.17667,39.14222,{"lat":52,"lon":51},[55,58],{"name":56,"role":34,"phone":35,"phoneExt":57,"email":40},"Chunyong Han, MD.","1174",{"name":59,"role":60,"phone":26,"phoneExt":26,"email":26},"Jian Yin, MD.","PRINCIPAL_INVESTIGATOR",{"type":62,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100507529",false,"NCT05888571","Pre-pectoral Breast Reconstruction With or Without Mesh","A Randomized Controlled Trial of Prepectoral Breast Reconstruction With and Without Mesh","Inclusion Criteria:\n\n1. Adult women aged 18-65 years who plan to undergo unilateral or bilateral immediate prepectoral prothesis breast reconstruction;\n2. SSM or NSM or Skin-Reducing Mastectomy for breast cancer patients or prophylactic mastectomy;\n3. Tissue expander size =\\\u003C800cc, implant size =\\\u003C600cc;\n4. The blood perfusion of breast skin flap was well;\n5. Do not smoking in the last 4 weeks or more\n6. Patients with normal expectations and mental health for breast reconstruction;\n7. Signed consent to participate\n\nExclusion Criteria:\n\n1. Poor perfusion of breast mastectomy flap;\n2. II stage breast reconstruction patients;\n3. History of chest radiotherapy;\n4. BMI greater than 35;\n5. Patients who have not quit smoking within the last 4 weeks;","FEMALE","18 Years","65 Years",{"count":73,"type":74},164,"ESTIMATED","INTERVENTIONAL",[77],"NA","To explore the efficacy and safety that occur after immediate prepectoral breast reconstruction when TiLOOP Mesh is used compared to that when TiLOOP Mesh is not used.",[80,81],"Prepectoral Breast Reconstruction","TiLOOP Mesh","2024-01-29",{"date":84,"type":85},"2024-01-31","ACTUAL",{"date":87,"type":85},"2023-07-01",{"date":89,"type":74},"2026-12",{"name":5,"class":6},1]