Health Trials

Prevalence of Human Papillomavirus (HPV) in a Healthy Population: A Feasibility Study of Oropharyngeal Cancer Screening

ConditionOropharynx Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40+
SponsorThe Institute of Molecular and Translational Medicine, Czech Republic

About this trial

This study defines the prevalence of oral infection with high-risk human papillomaviruses (hrHPV) in individuals over 40 years of age in the Czech Republic. It also establishes an effective methodology for oropharyngeal carcinoma screening and optimization of screening and testing procedures.

Eligibility criteria

Qualifiers

Participants aged 40 years or older at the time of enrollment.

Individuals who are capable of rinsing the oral cavity by gargling independently.

Signed informed consent for study participation, molecular-genetic testing, and personal data processing.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Self-sampling by gargling kit at dental clinic
  • Questionnaire
  • Self-sampling by gargling kit at home
  • Blood sampling
  • Self-sampling of the urogenital area

Treatment groups

20,000 Participants
are divided into 2 treatment groups

Locations

5
Masaryk Memorial Cancer Institute Brno Czechia
Stomatologická klinika, Fakultní nemocnice u sv. Anny Brno Czechia
Stomatologické centrum ARTDENT s.r.o.586 01, Jihlava Czechia
Klinika zubního lékařství Fakultní nemocnice Olomouc77900, Olomouc Czechia

Sponsors and collaborators

The Institute of Molecular and Translational Medicine, Czech Republic

Lead sponsor

National Institute for Cancer Research, Czech Republic

Collaborator

Source ClinicalTrials.gov