Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-36
SponsorCliniques universitaires Saint-Luc- Université Catholique de Louvain

About this trial

To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors. Having such a method at our disposal would enable us to better assess the risk to develop those defects and will help us provide new prevention and treatment strategies to ensure a healthy oral development.

The aims of this study are :

* Assess the caries risk in childhood cancer survivors compared with a control group. * Assess the dental development defects risk in childhood cancer survivors compared with a control group.

Eligibility criteria

Qualifiers

age below 10 at cancer diagnosis (for the CCS group).

Chemotherapy must have been used to treat the patient (For the CCS group).

The patient is 12 years old or older at the time of the follow-up appointment of the present study

Disqualifiers

A patient who was diagnosed and treated after 10 years old.

Patient below 12 years old at time of study recruitment

Patients with syndrome or diseases that involve teeth impairment*

Pregnant patient

Trial design

Treatments tested in this trial

  • Clinical and radiographic dental examination

Treatment groups

142 Participants
are divided into 2 treatment groups

Locations

1
Cliniques universitaires Saint-Luc1200, Brussels Belgium

Sponsors and collaborators

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Lead sponsor