[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636502":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":31,"collaborators":10,"id":35,"slug":10,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":38,"acronym":10,"eligibilityCriteria":39,"healthyVolunteers":36,"sex":40,"minAge":41,"maxAge":10,"enrollmentInfo":42,"targetDuration":10,"studyType":45,"phases":10,"briefSummary":46,"conditions":47,"keywords":10,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":60},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Knee Osteoarthritis Patients",null,"Adults aged 40 years and older diagnosed with knee osteoarthritis based on the American College of Rheumatology (ACR) criteria attending the Assiut University Trauma Hospital.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Esraa M.H Ibrahim","CONTACT","+201112969235","esraa.m.hosny@aun.edu.eg",[19],{"facility":20,"status":10,"city":21,"state":10,"zip":10,"country":22,"cosmosGeoPoint":23,"geoPoint":28,"contacts":29},"Assiut University Trauma Hospital","Asyut","Egypt",{"type":24,"coordinates":25},"Point",[26,27],31.18368,27.18096,{"lat":27,"lon":26},[30],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Esraa Mostafa Hosny Ibrahim","Assistant Lecturer","100636502",false,"NCT07566520","Prevalence of Sarcopenia and Its Associated Factors in Patients With Knee Osteoarthritis in a Tertiary Care Hospital in Upper Egypt","Inclusion Criteria:\n\n* Adults aged 40 years and older diagnosed with knee OA based on the American College of Rheumatology (ACR) criteria.\n* Patients who are willing to participate and provide informed written consent.Exclusion Criteria:\n* Inflammatory arthritis: patients with rheumatoid arthritis, gouty arthritis, or systemic lupus erythematosus (SLE) to avoid confusion with inflammatory muscle wasting.\n* Physical Limitations: amputees or those with severe physical deformities preventing gait speed tests or handgrip measurement.\n* Patients with cardiac pacemakers or implanted electronic devices (as these interfere with Bioelectrical Impedance Analysis (BIA)).\n* Severe Comorbidities: end-stage renal or hepatic disease, advanced malignancy or cachexia.\n* Severe neurological disorders (e.g., Parkinson's disease, Stroke with paralysis) that directly affect muscle mass and mobility.\n* Prolonged use of systemic corticosteroids (which cause secondary sarcopenia)","ALL","40 Years",{"count":43,"type":44},224,"ESTIMATED","OBSERVATIONAL","Osteoarthritis (OA) and sarcopenia are two highly prevalent, interconnected geriatric syndromes that often coexist, leading to a condition termed \"osteosarcopenia\". Globally, the pooled prevalence of sarcopenia in patients with knee OA is estimated at approximately 25.07%, significantly higher than in the general population.",[48,49],"Osteoarthritis","Sarcopenia","NOT_YET_RECRUITING","2026-04-27",{"date":53,"type":54},"2026-05-05","ACTUAL",{"date":56,"type":44},"2026-05",{"date":58,"type":44},"2027-07",{"name":5,"class":6},1]