[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614781":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":30,"locations":37,"responsibleParty":53,"collaborators":11,"id":55,"slug":11,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":11,"eligibilityCriteria":59,"healthyVolunteers":56,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":11,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":11,"overallStatus":72,"whyStopped":11,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Group","SHAM_COMPARATOR",null,[13],"Behavioral: Standard of care",{"label":15,"type":16,"description":11,"interventionNames":17},"MetaNeb Group","EXPERIMENTAL",[18],"Device: MetaNeb Therapy",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","MetaNeb Therapy","Patients in the MetaNeb group receive at least 4 sessions of MetaNeb therapy on postoperative day 1 (each session includes cycles of CPEP and CHFO modes totaling 10 minutes).",[15],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":11},"BEHAVIORAL","Standard of care","Standard postoperative care, including guidance on coughing and expectoration, turning and back percussion, and early mobilization (getting out of bed for physical activity).",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Minhui Dong","CONTACT","+86 02164041990","692959","dong.minhui@zs-hospital.sh.cn",[38],{"facility":39,"status":11,"city":40,"state":41,"zip":42,"country":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Zhongshan Hospital Fudan University","Shanghai","Shanghai Municipality","200030","China",{"type":45,"coordinates":46},"Point",[47,48],121.45806,31.22222,{"lat":48,"lon":47},[51],{"name":32,"role":33,"phone":52,"phoneExt":35,"email":36},"+86 021 64041990",{"type":54,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100614781",false,"NCT07284056","Prevention and Treatment of Early Postoperative Atelectasis Using The MetaNeb System in Patients Underwent Esophagectomy","Inclusion Criteria:\n\n1. Age between 18 and 85 years.\n2. Patients who are scheduled for ICU admission after esophagectomy for esophageal cancer.\n\nExclusion Criteria:\n\n1. Presence of an artificial airway at the time of ICU admission.\n2. Planned ICU stay less than 24 hours.\n3. Patients with contraindications to the use of the MetaNeb® System, or those unable to cooperate due to organic or psychiatric conditions.","ALL","18 Years","85 Years",{"count":64,"type":65},178,"ESTIMATED","INTERVENTIONAL",[68],"NA","The goal of this clinical trial is to evaluate whether the MetaNeb® System can effectively prevent and treat early postoperative atelectasis in adult patients admitted to ICU after esophagectomy for esophageal cancer.\n\nThe main question it aims to answer is: can the MetaNeb® system significantly reduce the lung ultrasound score (LUSS) indicating atelectasis on postoperative days 1 and 2? Participants will be randomly assigned to either the standard treatment or MetaNeb group, undergo lung ultrasound and electrical impedance tomography (EIT) assessments on postoperative days 1 and 2, receive at least 4 sessions of MetaNeb therapy on postoperative day 1 if in the intervention group, be monitored for oxygenation indices, ICU stay duration, incidence of mechanical ventilation, need for bronchoscopic intervention, and adverse events like pneumothorax.",[71],"Atelectases, Postoperative Pulmonary","NOT_YET_RECRUITING","2025-12-15",{"date":75,"type":76},"2025-12-16","ACTUAL",{"date":78,"type":65},"2026-01-01",{"date":80,"type":65},"2026-12-31",{"name":5,"class":6},1]