[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628357":3},{"organization":4,"outcomesModule":7,"designInfo":23,"detailedDescription":29,"studyPopulation":22,"armGroups":30,"interventions":37,"overallOfficials":22,"centralContacts":43,"locations":49,"responsibleParty":65,"collaborators":67,"id":71,"slug":22,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":22,"eligibilityCriteria":75,"healthyVolunteers":72,"sex":76,"minAge":77,"maxAge":22,"enrollmentInfo":78,"targetDuration":22,"studyType":81,"phases":82,"briefSummary":83,"conditions":84,"keywords":22,"overallStatus":86,"whyStopped":22,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Baylor Research Institute","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":22},[9,13],{"measure":10,"description":11,"timeFrame":12},"Prevalence of Coronary Atherosclerosis","The primary outcome is to determine the prevalence of coronary atherosclerosis in former high-intensity athletes using AI-guided software to analyze a CCTA.","At CCTA assessment",{"measure":14,"description":15,"timeFrame":16},"Coronary Atherosclerosis Characteristics","Determine the characteristics (burden, composition, risk features) of coronary atherosclerosis in former high-intensity athletes using AI-guided software to analyze a CCTA.","At CCTA Assessment",[18],{"measure":19,"description":20,"timeFrame":21},"Plaque Burden","The secondary outcome is to correlate plaque burden with biomarkers (Lipid panel, HbA1c).","Day of CCTA and biomarker collection",null,{"allocation":24,"interventionModel":25,"interventionModelDescription":22,"primaryPurpose":26,"observationalModel":22,"timePerspective":22,"maskingInfo":27},"NA","SINGLE_GROUP","SCREENING",{"masking":28,"maskingDescription":22,"whoMasked":22},"NONE","A prospective, interventional, single-center study to determine the prevalence and characteristics (burden, composition, risk features) of coronary atherosclerosis in former high-intensity athletes using AI-guided software to analyze a CCTA.",[31],{"label":32,"type":33,"description":34,"interventionNames":35},"Athletes","EXPERIMENTAL","This arm will have answer a questionnaire, have a physical exam performed as well as a Coronary CTA and labs completed. The Coronary CTA images will be analyzed using AI-software to assess plaque quantification and an ischemia analysis.",[36],"Device: Coronary CTA",[38],{"type":39,"name":40,"description":41,"armGroupLabels":42,"otherNames":22},"DEVICE","Coronary CTA","The Coronary CTA will be performed for each participant. These images will be analyzed using AI-software to assess plaque quantification and an ischemia analysis, if necessary.",[32],[44],{"name":45,"role":46,"phone":47,"phoneExt":22,"email":48},"Bonnie Ostergren","CONTACT","469-814-4181","bonnie.ostergren@bswhealth.org",[50],{"facility":51,"status":22,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Baylor Scott & White The Heart Hospital- Plano","Plano","Texas","75093","United States","US",{"type":58,"coordinates":59},"Point",[60,61],-96.69889,33.01984,{"lat":61,"lon":60},[64],{"name":45,"role":46,"phone":47,"phoneExt":22,"email":48},{"type":66,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR",[68],{"name":69,"class":70},"Cleerly, Inc.","INDUSTRY","100628357",false,"NCT07460583","ProActive Athlete Heart Program: Proposal for Cardiac Risk Screening in Former High-Intensity Athletes","Inclusion Criteria:\n\n* Former professional or collegiate high-intensity athletes (e.g., NFL alumni, Division I athletes, or equivalent competitive-level participants).\n* Age ≥30 years\n\nExclusion Criteria:\n\n* eGFR \\\u003C40 mL\u002Fmin\u002F1.73 m²\n* Known iodinated contrast allergy\n* Weight \\>450 lbs. (scanner table limit)\n* Inability to hold breath \\>10 seconds\n* Uncontrolled arrhythmia\n* Contraindication to beta-blocker, Calcium Channel Blockers and nitroglycerin\n* Taking part in another research study that has not given their permission to participate in this one\n* Pregnancy","ALL","30 Years",{"count":79,"type":80},100,"ESTIMATED","INTERVENTIONAL",[24],"AI-Guided Coronary CT Angiography Screening in Former High-Intensity Athletes",[85],"Coronary Atherosclerosis Due to Calcified Coronary Lesion","NOT_YET_RECRUITING","2026-04-30",{"date":89,"type":90},"2026-05-05","ACTUAL",{"date":92,"type":80},"2026-08-28",{"date":94,"type":80},"2027-01-31",{"name":5,"class":6},1]