[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639708":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":20,"collaborators":24,"id":26,"slug":11,"hasResults":27,"nctId":28,"briefTitle":29,"officialTitle":29,"acronym":11,"eligibilityCriteria":30,"healthyVolunteers":27,"sex":31,"minAge":32,"maxAge":33,"enrollmentInfo":34,"targetDuration":11,"studyType":37,"phases":38,"briefSummary":40,"conditions":41,"keywords":44,"overallStatus":47,"whyStopped":11,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":11},{"fullName":5,"class":6},"Babylon University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"periodontitis patients with pocket depth","EXPERIMENTAL",null,[13],"Procedure: scaling and root planing",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"PROCEDURE","scaling and root planing","Periodontitis patients (n = 21) will included in this clinical trial. Clinical periodontal parameters will recorded and GCF samples will collected from randomly selected 4-6 mm periodontal pockets at baseline (T0) as well as 4 weeks (T1) and 12 weeks (T2) after NSPT. GCF levels of β-catenin, 8-OHdG, and TAC will be assayed by enzyme linked immunosorbent assay (ELISA).",[9],{"type":21,"investigatorFullName":22,"investigatorTitle":23,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Zeyad Nazar","Assistant Professor",[25],{"name":5,"class":6},"100639708",false,"NCT07596667","Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial","Inclusion criteria:\n\n* patients over 18 years old\n* patients with periodontal pockets depth more than 4 mm\n\nExclusion criteria:\n\n* Pregnant women\n* patients taking antibiotic within the last three months\n* Patients with systemic disease ( Diabetes mellitus)","ALL","18 Years","60 Years",{"count":35,"type":36},21,"ESTIMATED","INTERVENTIONAL",[39],"NA","Background: To profile gingival crevicular fluid (GCF) β-Catenin, 8-OHdG, and total antioxidants capacity (TAC) in periodontitis patients during healing of periodontal pockets following non-surgical periodontal therapy (NSPT).Methods: Periodontitis patients (n = 21) will included in this clinical trial. Clinical periodontal parameters will recorded and GCF samples will collected from randomly selected 4-6 mm periodontal pockets at baseline (T0) as well as 4 weeks (T1) and 12 weeks (T2) after NSPT. GCF levels of β-catenin, 8-OHdG, and TAC will be assayed by enzyme linked immunosorbent assay (ELISA).",[42,43],"Periodontitis, Adult","Periodontal Diseases",[45,46],"periodontitis","non surgical periodontal therapy","NOT_YET_RECRUITING","2026-05-18",{"date":50,"type":51},"2026-05-19","ACTUAL",{"date":53,"type":36},"2026-07-15",{"date":55,"type":36},"2026-12-01",{"name":22,"class":6}]