[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100468487":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":30,"responsibleParty":46,"collaborators":20,"id":48,"slug":20,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":20,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":20,"enrollmentInfo":56,"targetDuration":20,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":33,"whyStopped":20,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Centre Leon Berard","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Metastatic\u002Fadvanced PDAC Patients","EXPERIMENTAL","Tumor samples",[13],"Biological: Tumor samples (archival FFPE and optional de novo biopsy) and blood samples",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BIOLOGICAL","Tumor samples (archival FFPE and optional de novo biopsy) and blood samples","Molecular screening",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Philippe CASSIER, MD, PhD","PRINCIPAL_INVESTIGATOR",[26],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","0426556833","philippe.cassier@lyon.unicancer.fr",[31],{"facility":32,"status":33,"city":34,"state":20,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Centre Léon Bérard","RECRUITING","Lyon","69373","France",{"type":38,"coordinates":39},"Point",[40,41],4.84789,45.74906,{"lat":41,"lon":40},[44],{"name":23,"role":27,"phone":45,"phoneExt":20,"email":29},"0426556835",{"type":47,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100468487",false,"NCT05380414","Profiling Program of Advanced\u002FMetastatic Pancreatic Cancer Patients","A Single-center, Prospective Profiling Program of Advanced\u002FMetastatic Pancreatic Cancer Patients","Inclusion Criteria:\n\n* Male or female patient \\> 18 years\n* metastatic or advanced PDAC\n* Patient pretreated with no more than one prior systemic chemotherapy for metastatic\u002Fadvanced disease (radiotherapy is not counted as a line of therapy).\n* Availability of an archival representative FFPE tumor sample from primary tumor (surgery or diagnostic biopsy) and\u002For from metastatic lesion if metastatic disease at initial diagnosis with associated pathology report from an archival tumor block.\n* Life expectancy \\> 3 months\n* PS score 0 or 1.\n\nExclusion Criteria:\n\n* Curative therapy available\n* Any condition contraindicated with blood sampling procedures required by the protocol.\n* Known additional malignancy that is progressing or requires active treatment. Exceptions include adequately treated basal cell carcinoma of the skin, squamous cell carcinoma of the skin, or in situ cervical cancer.\n* Any psychological, familial, geographic or social situation, according to the judgment of investigator, potentially preventing the provision of informed consent or compliance to study procedure.","ALL","18 Years",{"count":57,"type":58},750,"ESTIMATED","INTERVENTIONAL",[61],"NA","The proposal is to implement a molecular screening program for advanced\u002Fmetastatic pancreatic cancer patients before the initiation of 1st line treatment in order to allow a better selection of patients for rationale personalized medicine with targeted agents and\u002For combination involving a chemotherapy backbone.",[64,65],"Metastatic Pancreatic Cancer","Advanced Pancreatic Cancer",[18,67,68],"Genomic profiles","Transcriptomic profiles","2026-03-26",{"date":71,"type":72},"2026-03-31","ACTUAL",{"date":74,"type":72},"2022-07-01",{"date":76,"type":58},"2027-09-01",{"name":5,"class":6},1]