About this trial

The purpose of this prospective observational clinical cohort study is to develop a scientifically based approach to the prediction and early diagnosis of intestinal dysfunction in cardiac surgery patients.

The main questions that the study should answer:

What are the main risk factors for the development of intestinal dysfunction? What specific and non-specific biomarkers can predict the development of intestinal dysfunction? The study participants will be monitored from the moment of hospitalization until the end of their stay in a medical facility

Eligibility criteria

Qualifiers

Surgery on the heart and main vessels with a high risk of developing gastrointestinal dysfunction (according to literature data and our own retrospective study);

Patient's consent to participate in the study

Disqualifiers

Patient's refusal to participate in the study;

HIV infection in the patient;

Immunosuppressive therapy;

Oncological disease;

Trial design

Treatments tested in this trial

  • additional blood testing for specific and non-specific markers of intestinal dysfunction, ultrasound examination of abdominal organs and measurement of intra-abdominal pressure

Treatment groups

100 Participants
are divided into 4 treatment groups

Locations

1
Petrovsky National Research Centre of Surgery Moscow Russia

Sponsors and collaborators

Petrovsky National Research Centre of Surgery

Lead sponsor

Negovsky Reanimatology Research Institute

Collaborator

Lomonosov Moscow State University Medical Research and Educational Center

Collaborator