About this trial
The purpose of this prospective observational clinical cohort study is to develop a scientifically based approach to the prediction and early diagnosis of intestinal dysfunction in cardiac surgery patients.
The main questions that the study should answer:
What are the main risk factors for the development of intestinal dysfunction? What specific and non-specific biomarkers can predict the development of intestinal dysfunction? The study participants will be monitored from the moment of hospitalization until the end of their stay in a medical facility
Eligibility criteria
Qualifiers
Surgery on the heart and main vessels with a high risk of developing gastrointestinal dysfunction (according to literature data and our own retrospective study);
Patient's consent to participate in the study
Disqualifiers
Patient's refusal to participate in the study;
HIV infection in the patient;
Immunosuppressive therapy;
Oncological disease;
Trial design
Treatments tested in this trial
- additional blood testing for specific and non-specific markers of intestinal dysfunction, ultrasound examination of abdominal organs and measurement of intra-abdominal pressure
Treatment groups
Locations
1Sponsors and collaborators
Petrovsky National Research Centre of Surgery
Lead sponsor
Negovsky Reanimatology Research Institute
Collaborator
Lomonosov Moscow State University Medical Research and Educational Center
Collaborator