Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-90
SponsorGuowei Tu
About this trial
This project aims to detect novel biomarkers from preoperative and early postoperative serum and urine samples of patients to screen and analyze the risk factors for predicting adverse postoperative renal outcomes in high-risk patients in cardiac surgery.
Eligibility criteria
Qualifiers
age >70 years;
30 < estimated glomerular filtration rate (eGFR) <60 mL·min-1·1.73 m-2;
diabetes mellitus, proteinuria;
a history of congestive heart failure within the previous year;
Disqualifiers
pre-existing chronic kidney disease (preoperative estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2);
previous RRT before cardiac surgery;
present AKI at screening;
a history of kidney transplant or other kidney diseases;
Trial design
Treatments tested in this trial
- Standard care "bundle"
Treatment groups
No treatment groups listed
Locations
2Zhongshan hospital200032, ShanghaiShanghai Municipality, China
Zhongshan hospital, Fudan university200030, ShanghaiShanghai Municipality, China
Sponsors and collaborators
Guowei Tu
Lead sponsor
Shanghai Zhongshan Hospital
Sponsor institution
Source ClinicalTrials.gov