[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642717":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":23,"locations":11,"responsibleParty":29,"collaborators":11,"id":31,"slug":11,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":35,"acronym":11,"eligibilityCriteria":36,"healthyVolunteers":32,"sex":37,"minAge":38,"maxAge":11,"enrollmentInfo":39,"targetDuration":11,"studyType":42,"phases":43,"briefSummary":45,"conditions":46,"keywords":52,"overallStatus":60,"whyStopped":11,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":11},{"fullName":5,"class":6},"University Hospital Hradec Kralove","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Preventive ciNPWT","EXPERIMENTAL",null,[13],"Device: closed incision negative pressure wound therapy (ciNPWT)",{"label":15,"type":16,"description":11,"interventionNames":11},"Standard dressing","NO_INTERVENTION",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"DEVICE","closed incision negative pressure wound therapy (ciNPWT)","targeted prophylactic closed incision negative pressure wound therapy in clinical practice for patients with a high predicted risk of wound healing complications",[9],[24],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},"Klara Balcarova","CONTACT","+420731964956","klara.balcarova@fnhk.cz",{"type":30,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100642717",false,"NCT07645547","Prophylactic Use of ciNPWT in Gynecologic Laparotomy","Implementation of Prophylactic Negative Pressure Wound Therapy (ciNPWT) in High-Risk Patients in Gynecologic Oncology: A Prospective Feasibility Study and Nested Qualitative Analysis","Inclusion Criteria:\n\n* Adult female patients scheduled for planned abdominal surgery for gynecologic or gynecologic-oncologic indications.\n\nIdentification as \"high-risk\" for wound healing complications based on a clinical risk screening at admission.\n\nSigned informed consent.\n\nExclusion Criteria:\n\n* Failure to provide informed consent.","FEMALE","18 Years",{"count":40,"type":41},30,"ESTIMATED","INTERVENTIONAL",[44],"NA","This is a prospective, open-label, non-randomized interventional feasibility study with a nested qualitative analysis. The study exploratively verifies the feasibility of targeted prophylactic closed incision negative pressure wound therapy (ciNPWT) in clinical practice for patients with a high predicted risk of wound healing complications and compares the 30-day incidence of postoperative complications with standard dressing.\n\nParticipants will:\n\n* Get ciNPWT or standard dressing after planned laparotomy\n* Answer the questionairs about qualite of life\n* Will visit the clinic 30 days after surgery to see the final result",[47,48,49,50,51],"Surgical Site Infection (SSI)","Wound Healing Complication","Seroma","Hematoma","Dehiscence",[53,54,55,56,57,58,59],"ciNPWT","laparotomy","surgical site infection","SSI","feasibility","PROMs","ASEPSIS","NOT_YET_RECRUITING","2026-06-11",{"date":63,"type":64},"2026-06-12","ACTUAL",{"date":66,"type":41},"2026-07",{"date":68,"type":41},"2028-12",{"name":5,"class":6}]