[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100360929":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":35,"responsibleParty":65,"collaborators":18,"id":67,"slug":18,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":18,"enrollmentInfo":75,"targetDuration":18,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":38,"whyStopped":18,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Centre Hospitalier le Mans","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Diet group","EXPERIMENTAL","Diet follow-up to personalize a low-protein diet for each patient. All patients following a low protein diet one month or more compose the \"diet group\".",[13],"Other: low protein diet",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Patients who accepted to take part of the study but refused the low protein diet and patients who discontinued the diet on the first month compose the control group.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"low protein diet","Patients will be managed with a restricted protein intake (controlled protein diets with a mean target at 0.6 g \u002F kg \u002F day of protein, according to a choice of dietary approaches, adapted to the situation of each patient).",[9],[25],{"name":26,"affiliation":5,"role":27},"Giorgina Piccoli, MD","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Christelle Jadeau, PD","CONTACT","0 (33) 2 43 43 43 43","37 482","cjadeau@ch-lemans.fr",[36,54],{"facility":37,"status":38,"city":39,"state":18,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Pôle Santé Sarthe et Loir","RECRUITING","La Flèche","72200","France",{"type":43,"coordinates":44},"Point",[45,46],-0.07553,47.69815,{"lat":46,"lon":45},[49,53],{"name":50,"role":31,"phone":51,"phoneExt":18,"email":52},"Giorgina PICCOLI, PhD","02 44 71 30 30","gpiccoli@yahoo.it",{"name":50,"role":27,"phone":18,"phoneExt":18,"email":18},{"facility":55,"status":38,"city":56,"state":18,"zip":18,"country":41,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Centre Hospitalier Le Mans","Le Mans",{"type":43,"coordinates":58},[59,60],0.20251,48.0021,{"lat":60,"lon":59},[63,64],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},{"name":50,"role":27,"phone":18,"phoneExt":18,"email":18},{"type":66,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100360929",false,"NCT03979534","Protecting Kidneys Through a Low Protein Diet: A Stepwise Multiple-Choice System Approach","ProReRePro","Inclusion Criteria:\n\n* All adult patients followed on the unit for advanced CKD, with Kidney disease stage 4-5 or stage 3 with fast progression and without contraindications.\n\nExclusion Criteria:\n\n* Malnutrition or short life-expectancy\n* Patients aged less than 18 years old\n* Pregnant women,\n* Incapacity to complete the free-consent form,\n* Pateints refusing participation in the study,\n* Patients without healthcare coverage.","ALL","18 Years",{"count":76,"type":77},100,"ESTIMATED","INTERVENTIONAL",[80],"NA","Nephrology care continues to progress and recommendations are now focused on delaying as much as possible the need for renal replacement therapy (\"intent-to-defer\"strategy). Protein restriction is a valuable tool for stabilizing chronic kidney disease (CKD) and retarding the need for renal replacement therapy, but the best diet to be prescribed is still matter of discussion. This study is aimed at identifying implementation strategies for nutritional management of advanced CKD.",[83],"Chronic Kidney Diseases",[85,86,87,88,89,90],"low-protein diet","pre-dialysis","chronic kidney disease","nutritional care","start of dialysis","incremental dialysis","2026-06-30",{"date":93,"type":94},"2026-07-01","ACTUAL",{"date":96,"type":94},"2019-04-01",{"date":98,"type":77},"2028-04-01",{"name":5,"class":6},2]