About this trial
The rates of cognitive decline and dementia after stroke are disproportionately high. Strategies that can protect the brain early after the stroke event could reduce the future risk of cognitive decline and dementia in these patients. Although physical exercise is usually recommended after stroke, there is very little information about the protective effect of exercise implemented in early stages of recovery as a potential protective measure against cognitive decline and dementia risk in these patients. This study will investigate the effect of a multimodal exercise intervention implemented early after the stroke event on cognition and on a selected group of markers that can predict cognitive decline and dementia risk.
Eligibility criteria
Qualifiers
have had a first-ever ischemic/hemorrhagic stroke confirmed by MRI/CT 0-6 months prior to participation.
Able to independently walk at least 10 meters (assistive devices permitted) and capable of following instructions will be required.
Disqualifiers
Diagnosed with dementia
Medications that impact cognition
Absolute contraindications to exercise or MRI scanning
Significant disability (modified Rankin score >3)
Trial design
Treatments tested in this trial
- Multimodal Training
- Balance, Toning and Stretching
Treatment groups
Locations
2Sponsors and collaborators
McGill University
Lead sponsor
Jewish Rehabilitation Hospital
Collaborator
McMaster University
Collaborator
Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Collaborator
Montreal Neurological Institute and Hospital
Collaborator