[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566046":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":39,"responsibleParty":77,"collaborators":80,"id":86,"slug":11,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":87,"sex":93,"minAge":94,"maxAge":11,"enrollmentInfo":95,"targetDuration":11,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":11,"overallStatus":42,"whyStopped":11,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Helsinki University Central Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Loop ileostomy","EXPERIMENTAL",null,[13],"Procedure: Loop ileostomy",{"label":15,"type":16,"description":11,"interventionNames":17},"Loop colostomy","ACTIVE_COMPARATOR",[18],"Procedure: Loop colostomy",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"PROCEDURE","Patient undergoing anterior rectal resection will receive loop ileostomy",[9],{"type":21,"name":15,"description":25,"armGroupLabels":26,"otherNames":11},"Patient undergoing anterior rectal resection will receive loop colostomy",[15],[28],{"name":29,"affiliation":5,"role":30},"Ville Sallinen, MD, PhD","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":11,"email":36},"Laura Koskenvuo, MD, PhD","CONTACT","+358-9-4711","laura.koskenvuo@hus.fi",{"name":29,"role":34,"phone":35,"phoneExt":11,"email":38},"ville.sallinen@helsinki.fi",[40,53,65],{"facility":41,"status":42,"city":43,"state":11,"zip":11,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Helsinki University Hospital","RECRUITING","Helsinki","Finland",{"type":46,"coordinates":47},"Point",[48,49],24.93545,60.16952,{"lat":49,"lon":48},[52],{"name":33,"role":34,"phone":11,"phoneExt":11,"email":36},{"facility":54,"status":42,"city":55,"state":11,"zip":11,"country":44,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"Tampere University Hospital","Tampere",{"type":46,"coordinates":57},[58,59],23.78712,61.49911,{"lat":59,"lon":58},[62],{"name":63,"role":34,"phone":11,"phoneExt":11,"email":64},"Toni Seppälä, MD, PhD","toni.seppala@tuni.fi",{"facility":66,"status":42,"city":67,"state":11,"zip":11,"country":44,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Turku University Hospital","Turku",{"type":46,"coordinates":69},[70,71],22.26869,60.45148,{"lat":71,"lon":70},[74],{"name":75,"role":34,"phone":11,"phoneExt":11,"email":76},"Pirita Varpe, MD, PhD","pirita.varpe@tyks.fi",{"type":30,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Ville Sallinen","Adj. Professor",[81,84],{"name":82,"class":83},"Mary and Georg Ehrnrooth's foundation","UNKNOWN",{"name":85,"class":83},"Helsinki University Hospital Research Funds","100566046",false,"NCT06650085","Protective Ileostomy Versus Protective Colostomy in Anterior Rectal Resection","PROtective ileoStomy Versus ProtectivE Colostomy in Anterior Rectal resectIon - a Multicenter, Open-label, Randomized conTrolled studY (PROSPERITY)","PROSPERITY","Inclusion Criteria: Patients undergoing anterior resection (resection of the rectum and colorectal or coloanal anastomosis) due to a rectal tumour and a protective stoma is planned.\n\nThe exclusion criteria are: (1) patient already having a stoma (or another stoma made during surgery), (2) technical inability to create ileo- or colostomy (e.g. previous bowel resection, anatomical factors), (3) age \\\u003C18 years, (4) inadequate ability to co-operate.","ALL","18 Years",{"count":96,"type":97},350,"ESTIMATED","INTERVENTIONAL",[100],"NA","Loop ileostomy and loop colostomy are both used as protective stomas after anterior resection. There is a lack of evidence on the superiority of loop ileostomy versus loop colostomy. This is a multicenter, open-label, superiority, individually randomized controlled trial including patients undergoing anterior rectal resection with primary anastomosis and a protective stoma. Patients scheduled for anterior rectal resection are randomized 1:1 to loop ileostomy or loop colostomy intraoperatively. Primary outcome is cumulative stoma-related adverse events within 60 days post-primary surgery (scored using Comprehensive Complication Index (CCI)).",[103,104],"Stoma Colostomy","Stoma Ileostomy","2026-06-05",{"date":107,"type":108},"2026-06-09","ACTUAL",{"date":110,"type":108},"2025-10-06",{"date":112,"type":97},"2033-10",{"name":5,"class":6},3]