[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100377761":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":40,"locations":50,"responsibleParty":78,"collaborators":80,"id":83,"slug":10,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":10,"enrollmentInfo":92,"targetDuration":10,"studyType":95,"phases":10,"briefSummary":96,"conditions":97,"keywords":102,"overallStatus":66,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Centre hospitalier de l'Université de Montréal (CHUM)","OTHER",[8,14,18,22,26],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group",null,"Healthy, normal ocular surface",[13],"Diagnostic Test: Tear sample collection via Schirmer strip and subsequent analysis by mass spectrometry",{"label":15,"type":10,"description":16,"interventionNames":17},"Dry eye syndrome","Patients suffering from either:\n\n* Lacrimal insufficiency\n* Anterior blepharitis\n* Posterior blepharitis\n* Sjögren syndrome",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Allergic conjunctivitis","Patients suffering from allergic conjunctivitis",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Mucous membrane pemphigoid","Patients suffering from mucous membrane pemphigoid",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"Infectious keratoconjunctivitis","Patients suffering from keratitis and\u002For conjunctivitis of various etiology:\n\n* Viral\n* Bacterial\n* Fungal\n* Acanthamoeba",[13],[31],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"DIAGNOSTIC_TEST","Tear sample collection via Schirmer strip and subsequent analysis by mass spectrometry","During regular consultations at the ophthalmology department of the CHUM, eligible patients will undergo a standard 5 minute Schirmer tear test. The Schirmer strips will serve as tear samples and will be sent to UQAM's Department of chemistry for mass spectrometry analysis.",[19,9,15,27,23],[37],{"name":38,"affiliation":5,"role":39},"Marie-Claude Robert, MD, M.Sc","PRINCIPAL_INVESTIGATOR",[41,45],{"name":38,"role":42,"phone":43,"phoneExt":10,"email":44},"CONTACT","514-890-8278","marie-claude.robert.2@umontreal.ca",{"name":46,"role":42,"phone":47,"phoneExt":48,"email":49},"Marie-Catherine Tessier","514-890-8000","11550","marie-catherine.tessier.chum@ssss.gouv.qc.ca",[51,64],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":10},"Université du Québec à Montréal (UQAM) - Department of Chemistry","ACTIVE_NOT_RECRUITING","Montreal","Quebec","H2X 2J6","Canada",{"type":59,"coordinates":60},"Point",[61,62],-73.58781,45.50884,{"lat":62,"lon":61},{"facility":65,"status":66,"city":54,"state":55,"zip":67,"country":57,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"Centre Hospitalier de l'Université de Montréal (CHUM)","RECRUITING","H2X 3E4",{"type":59,"coordinates":69},[61,62],{"lat":62,"lon":61},[72,73,74,75],{"name":38,"role":42,"phone":43,"phoneExt":10,"email":44},{"name":46,"role":42,"phone":47,"phoneExt":48,"email":49},{"name":38,"role":39,"phone":10,"phoneExt":10,"email":10},{"name":76,"role":77,"phone":10,"phoneExt":10,"email":10},"Simon Trottier","SUB_INVESTIGATOR",{"type":79,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[81],{"name":82,"class":6},"Université du Québec a Montréal","100377761",false,"NCT04198740","Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface","EML-MSO","Inclusion Criteria:\n\n* Patients with healthy corneas or suffering from one of these pathologies:\n\nDry eye syndrome; Infectious keratitis and\u002For conjunctivitis; Mucous membrane pemphigoid; Allergic conjunctivitis.\n\nExclusion Criteria:\n\n* Patients younger than 18 years old;\n* Patients incapable of giving informed consent.",true,"ALL","18 Years",{"count":93,"type":94},300,"ESTIMATED","OBSERVATIONAL","This study aims to obtain the lacrimal fingerprint for frequent pathologies of the ocular surface and establish a normative base for each of them.",[98,99,100,101],"Dry Eye Syndrome","Infectious Keratoconjunctivitis","Mucous Membrane Pemphigoid","Allergic Conjunctivitis",[103,104,105,106],"Lacrimal fingerprint","Metabolomics","Proteomics","Ocular surface","2026-04-23",{"date":109,"type":110},"2026-04-27","ACTUAL",{"date":112,"type":110},"2020-02-01",{"date":114,"type":94},"2035-01",{"name":5,"class":6},2]