Proximal Row Carpectomy vs Four-corner Fusion for Osteoarthritis of the Wrist

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorTöölö Hospital

About this trial

Study purpose is to compare the outcome after proximal row carpectomy (PRC) vs four-corner fusion (FCA) for SLAC/SNAC II-III type osteoarthritis (OA) in a double-blinded randomized controlled study setting.

Patients with radiologically and clinically confirmed OA are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo either PRC or FCA. The study will be patient and assessor blinded.

Baseline data is collected preoperatively and is followed by a follow-up visits at 2 and 6 weeks, 3, 6, 12 months, and 5, 10 years after the intervention. Unveiling of the allocation is at 12 months post-intervention.

Eligibility criteria

Qualifiers

SLAC/SNAC II-III

Age 18 - 75

Symptom duration > 3 months

American Society of Anaesthesiologists physical status (ASA) I-II

Disqualifiers

Patient eligible for SL reconstruction or scaphoid

Ulnocarpal/pancarpal arthritis

Lunate fossa, proximal lunate arthrosis or both

Age <18 or >75 years

Trial design

Treatments tested in this trial

  • Proximal Row Carpectomy
  • Four-corner fusion

Treatment groups

84 Participants
are divided into 2 treatment groups

Locations

5
Töölö Hospital (Helsinki University Hospital) Helsinki Finland
Central Hospital of Central Finland Jyväskylä Finland
Kymenlaakso Central Hospital Kotka Finland
Tampere University Hospital Tampere Finland

Sponsors and collaborators

Töölö Hospital

Lead sponsor

Tampere University Hospital

Collaborator

Turku University Hospital

Collaborator

Jyväskylä Central Hospital

Collaborator

Kymenlaakso Central Hospital Kotka Finland

Collaborator