[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579293":3},{"organization":4,"armGroups":7,"interventions":53,"overallOfficials":58,"centralContacts":63,"locations":69,"responsibleParty":129,"collaborators":131,"id":138,"slug":10,"hasResults":139,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":10,"eligibilityCriteria":143,"healthyVolunteers":144,"sex":145,"minAge":10,"maxAge":10,"enrollmentInfo":146,"targetDuration":149,"studyType":150,"phases":10,"briefSummary":151,"conditions":152,"keywords":166,"overallStatus":72,"whyStopped":10,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":177,"completionDateStruct":179,"leadSponsor":181,"locationsCount":182},{"fullName":5,"class":6},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",[8,14,18,22,26,29,33,37,41,45,49],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal Physiology",null,"Patients without cancers or precancerous lesion",[13],"Other: No Interventions",{"label":15,"type":10,"description":16,"interventionNames":17},"Colorectal Cancer","Patients diagnosed with colorectal cancer (Pre-intervention)",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Gastric Cancer","Patients diagnosed with gastric cancer (Pre-intervention)",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Hepatic Cancer","Patients diagnosed with hepatic cancer (Pre-intervention)",[13],{"label":27,"type":10,"description":28,"interventionNames":10},"Oesophageal","Patients diagnosed with oesophageal cancer (Pre-intervention)",{"label":30,"type":10,"description":31,"interventionNames":32},"Pancreatic Cancer","Patients diagnosed with pancreatic cancer (Pre-intervention)",[13],{"label":34,"type":10,"description":35,"interventionNames":36},"Gastric Ulcer","Patients with gastric ulcers without any cancer",[13],{"label":38,"type":10,"description":39,"interventionNames":40},"Colorectal Adenoma","Patients 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0791-86300410","xiaozhongwangncu@163.com",{"facility":100,"status":72,"city":101,"state":102,"zip":103,"country":76,"cosmosGeoPoint":104,"geoPoint":108,"contacts":109},"Huashan Hospital Affiliated to Fudan University","Shanghai","Shanghai Municipality","200040",{"type":78,"coordinates":105},[106,107],121.45806,31.22222,{"lat":107,"lon":106},[110],{"name":111,"role":66,"phone":112,"phoneExt":10,"email":113},"Ming Guan","+86 19901643902","guanming88@yahoo.com",{"facility":115,"status":72,"city":116,"state":117,"zip":118,"country":76,"cosmosGeoPoint":119,"geoPoint":123,"contacts":124},"The Second Affiliated Hospital of Zhejiang University School of Medicine","Hangzhou","Zhejiang","310009",{"type":78,"coordinates":120},[121,122],120.16142,30.29365,{"lat":122,"lon":121},[125],{"name":126,"role":66,"phone":127,"phoneExt":10,"email":128},"Kefeng Ding","+86 13906504783","dingkefeng@zju.edu.cn",{"type":130,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[132,134,136],{"name":133,"class":6},"The First Affiliated Hospital of Nanchang University",{"name":135,"class":6},"Second Affiliated Hospital of Nanchang University",{"name":137,"class":6},"Huashan Hospital","100579293",false,"NCT06822413","Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis","A Novel Raman Spectroscopy-Based Method for Pan-Cancers Early Diagnosis Supported by Deep Learning: A Prospective, Single-Arm, Multicentre Study","Inclusion Criteria:\n\n* Histopathological diagnosis of malignant tumors, including colorectal cancer, gastric cancer, hepatic cancer, pancreatic cancer, and esophageal cancer.\n* Patients in normal physiological conditions without any malignant tumors or precancerous lesions.\n* Patients with malignant tumor without recieving any interventions, including chemotherapy, surgery, radiotherapy, immunotherapy or other anti-tumor treatments.\n* Patients with a histopathological diagnosis of any precancerous lesions or non-malignant disease.\n\nExclusion Criteria:\n\n* Patients with metastatic tumors or in the condition with two or more kinds of malignant tumors at the same time\n* Post-cancer treatment patients.",true,"ALL",{"count":147,"type":148},600,"ESTIMATED","1 Year","OBSERVATIONAL","The goal of this observational study is to explore whether a Raman-based, deep learning-assisted approach can be used to develop an effective method for early pan-cancer screening. The study includes healthy individuals, patients at risk of cancer, and patients with diagnosed cancers. The main questions it aims to answer are:\n\n* Evaluating the deep-learning model's accuracy and specificity in identifying cancer-specific features in Raman spectral data and determining whether this method can accurately classify patients based on risk.\n* Identifying which model is more adaptable to the Raman spectrum\n* Providing an interpretable analysis of the model-generated diagnosis Participants are already being diagnosed and follow-up to determine the type of cancer.",[153,154,155,156,157,9,158,159,160,161,162,163,46,164,34,50,165],"Cancer Diagnosis","Liver Cancer, Adult","Cancer Screening","Colorectal Cancer (CRC)","Gastric Cancers","Pancreatic Cancer, Adult","Raman Spectroscopy","Deep Learning Model","Esophageal Cancer","Malignant Tumours","Precancerous Conditions","Adenoma Colon Polyp","Cirrhoses, Liver",[167,168,155,159,15,30,19,161,169,170,46,38,171,50,172],"Pan-cancer","Deep Learning Models","malignant tumour","Precancerous Condtions","Gastirc Ulcer","Cirrhoses","2025-04-19",{"date":175,"type":176},"2025-04-24","ACTUAL",{"date":178,"type":176},"2022-09-01",{"date":180,"type":148},"2025-07-28",{"name":5,"class":6},4]