Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBrigham and Women's Hospital

About this trial

This single-center, 400-patient, randomized controlled trial assesses the impact of a patient- and provider-facing EPIC Best Practice Advisory (BPA; alert-based computerized decision support tool) to increase guideline-directed utilization of statin and statin-alternative oral LDL-C lowering therapies in patients with PAD who are not being prescribed LDL-C-lowering therapy.

Eligibility criteria

Qualifiers

All patients ≥ 18 years old

Seen in Cardiovascular Medicine Clinic, Primary Care, Podiatry, Vascular Surgery, and Diabetology

Medical history entry, visit diagnosis, or problem list entry of PAD

Not prescribed LDL-C-lowering therapy

Disqualifiers

Patients taking a statin, ezetimibe, bempedoic acid, a PCSK9 inhibitor, inclisiran or a combination will be excluded

Trial design

Treatments tested in this trial

  • Computer Alert

Treatment groups

400 Participants
are divided into 2 treatment groups

Locations

1
Brigham and Women's Hospital02115, BostonMassachusetts, United States

Sponsors and collaborators

Brigham and Women's Hospital

Lead sponsor

Esperion Therapeutics, Inc.

Collaborator