[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588251":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":23,"locations":29,"responsibleParty":82,"collaborators":12,"id":86,"slug":12,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":87,"sex":93,"minAge":94,"maxAge":12,"enrollmentInfo":95,"targetDuration":12,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":32,"whyStopped":12,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","Participants allocated to the control group will receive standard care. No restrictions regarding physical activity will be imposed.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Exercise training","EXPERIMENTAL","Participants allocated to the exercise intervention group will receive standard care plus an exercise intervention. The exercise intervention will of consist moderate-to-high intensity supervised and unsupervised home-based exercise training (bicyling, walking, or running) 5 times\u002Fweek for 18 weeks. After the initial 18-week intervention period, participants will be given the option to continue the intervention until week 162.",[18],"Other: Exercise training",[20],{"type":6,"name":14,"description":21,"armGroupLabels":22,"otherNames":12},"Participants allocated to the exercise intervention group will receive standard care plus an exercise intervention. The exercise intervention will consist moderate-to-high intensity supervised and unsupervised home-based exercise training (bicyling, walking, or running) 5 times\u002Fweek for 18 weeks.",[14],[24],{"name":25,"role":26,"phone":27,"phoneExt":12,"email":28},"Casper Simonsen, Phd","CONTACT","+45 35 45 76 41","casper.simonsen@regionh.dk",[30,45,59,70],{"facility":31,"status":32,"city":33,"state":12,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Centre for Physical Activity Research, Copenhagen Univerisity Hospital - Rigshospitalet","RECRUITING","Copenhagen","2100","Denmark",{"type":37,"coordinates":38},"Point",[39,40],12.56553,55.67594,{"lat":40,"lon":39},[43],{"name":44,"role":26,"phone":27,"phoneExt":12,"email":28},"Casper Simonsen, PhD",{"facility":46,"status":32,"city":47,"state":12,"zip":48,"country":35,"cosmosGeoPoint":49,"geoPoint":53,"contacts":54},"Herlev and Gentofte Hospital","Herlev","2730",{"type":37,"coordinates":50},[51,52],12.43998,55.72366,{"lat":52,"lon":51},[55],{"name":56,"role":26,"phone":57,"phoneExt":12,"email":58},"Louise Lang Lehrskov","0045 38689394","louise.lang.lehrskov.01@regionh.dk",{"facility":60,"status":32,"city":61,"state":12,"zip":62,"country":35,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"North Zealand University Hospital, Hillerød","Hillerød","3400",{"type":37,"coordinates":64},[65,66],12.30081,55.92791,{"lat":66,"lon":65},[69],{"name":56,"role":26,"phone":12,"phoneExt":57,"email":58},{"facility":71,"status":32,"city":72,"state":12,"zip":73,"country":35,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"Zealand University Hospital, Roskilde","Roskilde","4000",{"type":37,"coordinates":75},[76,77],12.08035,55.64152,{"lat":77,"lon":76},[80],{"name":56,"role":26,"phone":81,"phoneExt":12,"email":58},"35457641",{"type":83,"investigatorFullName":84,"investigatorTitle":85,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Casper Simonsen","Group Leader","100588251",false,"NCT06938971","Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)","Effects of Exercise Training on Health-related Quality of Life in Patients With Unresectable Metastatic Colorectal Cancer: A Multi-center Randomized Controlled Trial","REACH","Inclusion criteria:\n\n\\- Adults (≥18 years of age) schduled to undergo first-line chemotherapy for the treatment of metastatic colorectal cancer.\n\nExclusion criteria :\n\n* Pregnancy.\n* A life expectancy of \\\u003C 6 months.\n* Absolute contraindications to maximal exercise, as per the recommendations by the Danish Society of Cardiology.\n* ECOG (Eastern Cooperative Oncology Group) performance status \\> 2.\n* Inability to understand the Danish or English language.\n* Engagement in structured moderate-to-high aerobic exercise training for \\>30 min \\>1 times\u002Fweek for the past 3 months at the time of inclusion.","ALL","18 Years",{"count":96,"type":97},150,"ESTIMATED","INTERVENTIONAL",[100],"NA","The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with mCRC undergoing first-line chemotherapy.",[103],"Metastatic Colorectal Cancer (mCRC)",[105,106,107,108,109,110,111],"Exercise","Physical activity","Metastatic colorectal cancer","Colorectal cancer","Endurance training","Oncology","Chemotherapy","2026-05-08",{"date":114,"type":115},"2026-05-13","ACTUAL",{"date":117,"type":115},"2025-05-16",{"date":119,"type":97},"2030-05-01",{"name":5,"class":6},4]