[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555124":3},{"organization":4,"outcomesModule":7,"designInfo":26,"detailedDescription":34,"studyPopulation":25,"armGroups":35,"interventions":47,"overallOfficials":54,"centralContacts":59,"locations":69,"responsibleParty":87,"collaborators":25,"id":89,"slug":25,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":25,"eligibilityCriteria":94,"healthyVolunteers":90,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":25,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":25,"overallStatus":71,"whyStopped":25,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Affiliated Hospital of Nantong University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":21,"otherOutcomes":25},[9,13,17],{"measure":10,"description":11,"timeFrame":12},"Blood oxygen saturation before and after sputum aspiration","The degree of binding between oxygen and hemoglobin (Hb) in arterial blood","Not exceeding 1 day",{"measure":14,"description":15,"timeFrame":16},"Suctioning time","All time required for sputum suction process","Not exceeding 2 minute",{"measure":18,"description":19,"timeFrame":20},"Degree of airway bleeding","Use a disposable sputum collection device to aspirate sputum for patients and differentiate the blood content under a blue LED light.","Not exceeding 30 minute",[22],{"measure":23,"description":24,"timeFrame":12},"Patient family satisfaction","After suctioning, use a satisfaction questionnaire to survey the operating nurses, with a minimum score of 1 and a maximum score of 5. The higher the value, the higher the satisfaction.",null,{"allocation":27,"interventionModel":28,"interventionModelDescription":25,"primaryPurpose":29,"observationalModel":25,"timePerspective":25,"maskingInfo":30},"RANDOMIZED","CROSSOVER","SUPPORTIVE_CARE",{"masking":31,"maskingDescription":25,"whoMasked":32},"SINGLE",[33],"PARTICIPANT","Research content: (1) Selection and placement methods of oropharyngeal ventilation tubes, studying the application effects of different models and sizes of oropharyngeal ventilation tubes in critically ill patients, exploring the best placement method to improve the efficiency and safety of sputum suction operations. (2) The norms and techniques of sputum suction, the steps, techniques, and precautions of sputum suction, the depth, strength, time of insertion, and when to interrupt negative pressure, in order to minimize damage to the patient's respiratory mucosa. (3) Evaluation of patient comfort and tolerance, assessing the tolerance and potential adverse reactions of critically ill patients during oral pharyngeal intubation for sputum suction, providing a basis for optimizing sputum suction. (4) Evaluation of sputum suction effect, comparing blood oxygen saturation, respiratory distress, sputum sounds, and other indicators before and after sputum suction to evaluate the effectiveness of sputum suction.",[36,43],{"label":37,"type":38,"description":39,"interventionNames":40},"Intermittent negative pressure sputum suction through oral pharyngeal airway","EXPERIMENTAL","(1) Insert the oropharyngeal airway parallel into the oral cavity; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) The suction tube is inserted into the deep oral cavity through the middle lumen of the oropharyngeal airway; (4) Intermittent negative pressure for suction and suction of sputum",[41,42],"Procedure: continuous negative pressure suction","Procedure: Intermittent negative pressure sputum suction through oral pharyngeal airway",{"label":44,"type":45,"description":46,"interventionNames":25},"continuous negative pressure suction","NO_INTERVENTION","(1) Use a tongue depressor to open the mouth; (2) Lubricating the front end of the sputum suction tube with paraffin oil; (3) Insert a suction tube into the oral cavity to aspirate phlegm.",[48,52],{"type":49,"name":44,"description":50,"armGroupLabels":51,"otherNames":25},"PROCEDURE","(1) Open the mouth with a tongue depressor; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) Insert a suction tube into the mouth to aspirate phlegm.",[37],{"type":49,"name":37,"description":39,"armGroupLabels":53,"otherNames":25},[37],[55],{"name":56,"affiliation":57,"role":58},"Tao Zhang, MD","Ethics Committee of Nantong University Affiliated Hospital","STUDY_CHAIR",[60,65],{"name":61,"role":62,"phone":63,"phoneExt":25,"email":64},"Honglei Wu, MS","CONTACT","+8613862749927","wu_honglei@163.com",{"name":66,"role":62,"phone":67,"phoneExt":25,"email":68},"You Lu, BS","+8613962910607","490944983@qq.com",[70],{"facility":5,"status":71,"city":72,"state":73,"zip":74,"country":75,"countryCode":76,"cosmosGeoPoint":77,"geoPoint":82,"contacts":83},"RECRUITING","Nantong","Jiangsu","226001","China","CN",{"type":78,"coordinates":79},"Point",[80,81],120.87472,32.03028,{"lat":81,"lon":80},[84,85],{"name":61,"role":62,"phone":63,"phoneExt":25,"email":64},{"name":86,"role":62,"phone":25,"phoneExt":25,"email":25},"MS",{"type":88,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100555124",false,"NCT06508008","Rapid and Safe Sputum Suction Method Validation","Verification of the Effect of Intermittent Negative Pressure Sputum Suction Through Oral Pharyngeal Ventilation Tube in Comatose Patients","Inclusion Criteria:\n\n* 1\\. Clinical diagnosis of stroke; 2. Clinical diagnosis of comatose;\n\nExclusion Criteria:\n\n* 1\\. Clinical diagnosis of multiple organ failure; 2. Clinical diagnosis of multiple organ bleeding;","ALL","20 Years","90 Years",{"count":99,"type":100},900,"ESTIMATED","INTERVENTIONAL",[103],"NA","600 comatose patients admitted to the hospital in China from June 2024 to June 2028 were randomly divided into groups A and B. Group A used intermittent negative pressure suction through oral and pharyngeal ventilation, while group B used continuous negative pressure suction through regular oral and nasal suction.",[106],"Sputum","2024-07-12",{"date":109,"type":110},"2024-07-18","ACTUAL",{"date":112,"type":110},"2024-02-18",{"date":114,"type":100},"2024-08-18",{"name":5,"class":6},1]