[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100564088":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":18,"responsibleParty":45,"collaborators":47,"id":50,"slug":7,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":7,"enrollmentInfo":59,"targetDuration":7,"studyType":62,"phases":7,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":20,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Maastricht University Medical Center","OTHER",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Anna Wijen, Msc.","CONTACT","+31 626882868","anna.wijen@maastrichtuniversity.nl",{"name":15,"role":11,"phone":16,"phoneExt":7,"email":17},"Paul Savelkoul, Prof. Dr.","+31 433876610","paul.savelkoul@mumc.nl",[19],{"facility":5,"status":20,"city":21,"state":22,"zip":23,"country":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"RECRUITING","Maastricht","Limburg","6229 HX","Netherlands",{"type":26,"coordinates":27},"Point",[28,29],5.68889,50.84833,{"lat":29,"lon":28},[32,35,37,38,39,41,43],{"name":33,"role":11,"phone":34,"phoneExt":7,"email":13},"Anna Wijen, Msc","0031626882868",{"name":15,"role":11,"phone":36,"phoneExt":7,"email":17},"0031433876644",{"name":15,"role":11,"phone":7,"phoneExt":7,"email":7},{"name":33,"role":11,"phone":7,"phoneExt":7,"email":7},{"name":40,"role":11,"phone":7,"phoneExt":7,"email":7},"Christian von Wintersdorff, Dr.",{"name":42,"role":11,"phone":7,"phoneExt":7,"email":7},"Rob Driessen, Dr.",{"name":44,"role":11,"phone":7,"phoneExt":7,"email":7},"Dennis Bergmans, Dr.",{"type":46,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[48],{"name":49,"class":6},"Health Holland","100564088",false,"NCT06624618","Rapid Molecular Diagnosis of Sepsis in the Intensive Care Unit","Rapid Molecular Detection of Sepsis in Whole Blood","RADOS","Inclusion Criteria:\n\n-Patients are included when routine blood cultures are ordered for diagnosis of bloodstream infections.\n\nExclusion Criteria:\n\n-N\u002FA","ALL","18 Years",{"count":60,"type":61},300,"ESTIMATED","OBSERVATIONAL","Rapid diagnosis of sepsis is crucial for treatment and survival. Currently, blood culture takes 48 hours-5 days to complete. After starting antimicrobial treatment blood culture results are not reliable. As a result, empirical broad spectrum antimicrobial therapy is mostly used. This implies possible antimicrobial over- or under treatment which is associated with increased antimicrobial resistance development. Early identification of the causative pathogen of sepsis will therefore have a major impact on the adequate treatment and reduction of high mortality rates. To date, there is not a single molecular diagnostic test available on the market to detect all putative causative bacterial pathogens of sepsis. In this study, the investigators will develop and validate a completely new molecular sepsis approach based on pathogen DNA detection, as an alternative to culture.",[65,66],"Sepsis","Bloodstream Infection",[68,69,70,65,71,72],"Culture-free","Whole blood","Molecular diagnosis","Bloodstream infection","Bacterial DNA","2024-10-01",{"date":75,"type":76},"2024-10-03","ACTUAL",{"date":78,"type":76},"2024-05-01",{"date":80,"type":61},"2026-05-01",{"name":5,"class":6},1]