[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570874":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":24,"studyPopulation":13,"armGroups":25,"interventions":32,"overallOfficials":38,"centralContacts":42,"locations":48,"responsibleParty":67,"collaborators":13,"id":70,"slug":13,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":13,"studyType":82,"phases":83,"briefSummary":84,"conditions":85,"keywords":89,"overallStatus":51,"whyStopped":13,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Stanford University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":14},[9],{"measure":10,"description":11,"timeFrame":12},"Change in Compulsive Acquisition Scale (CAS)","The Compulsive Acquisition Scale (CAS) is an 18-item questionnaire that measures the extent to which individuals acquire and feel compelled to acquire possessions.\n\nThe total score (sum of 18 items) ranges from 0 to 126. Total score higher than 48 shows significant difficulty with acquiring.","Change from baseline to 3 weeks after treatment starts",null,[15],{"measure":16,"description":17,"timeFrame":12},"Change in Hoarding Symptom Severity as Measured by Saving Inventory-Revised (SI-R)","The Saving Inventory-Revised scale (SI-R) is a 23-item questionnaire with 3 factor-analytically defined sub-scales for difficulty discarding, excessive clutter, and compulsive acquisition.\n\nThe total score (sum of 23 items) ranges from 0 to 92. Total score higher than 41 shows significant difficulty with clutter.\n\nFor the acquisition subscale, items 2 (reverse score), 9, 11, 14, 16, 18 and 21 are summed together. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with excessive acquisition.\n\nFor the difficulty discarding subscale, items 4(reverse score), 6, 7, 13, 17, 19, 23 are summed together. The subscale ranges from 0 to 28 and score greater than 13 indicates difficulty with discarding.\n\nFor the clutter subscale, items 1, 3, 5, 8, 10, 12, 15, 20, 22 are summed together. The subscale ranges from 0 to 36 and score greater than 15 indicates difficulty with accumulated clutter.",{"allocation":19,"interventionModel":20,"interventionModelDescription":13,"primaryPurpose":21,"observationalModel":13,"timePerspective":13,"maskingInfo":22},"NA","SINGLE_GROUP","TREATMENT",{"masking":23,"maskingDescription":13,"whoMasked":13},"NONE","Hoarding disorder (HD) is characterized by difficulty letting go of possessions, leading to clutter that congests living spaces and impairs daily functioning. The majority of HD patients treated with cognitive behavioral therapy for HD usually experience considerable residual symptoms. New treatments are greatly needed. This study explores whether rapid non-invasive brain stimulation can help reduce hoarding disorder symptoms.",[26],{"label":27,"type":28,"description":29,"interventionNames":30},"Theta-burst stimulation (TBS)","EXPERIMENTAL","Theta-burst stimulation (a form of transcranial magnetic stimulation) targeting the right frontal pole.",[31],"Device: MagPro X100 by MagVenture",[33],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":13},"DEVICE","MagPro X100 by MagVenture","Participants will receive 5 session per day of TBS for 6 days (30 sessions total). Six treatment days have to occur within a 2 week period. Each session will be comprised of 1800 pulses, using a MagVenture MagPro X100.",[27],[39],{"name":40,"affiliation":5,"role":41},"Carolyn I Rodriguez, MD, PhD","PRINCIPAL_INVESTIGATOR",[43],{"name":44,"role":45,"phone":46,"phoneExt":13,"email":47},"Paula Munoz Rodriguez, PhD","CONTACT","650-723-4095","clutterhelp@stanford.edu",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Stanford University Medical Center","RECRUITING","Palo Alto","California","94305","United States","US",{"type":58,"coordinates":59},"Point",[60,61],-122.14302,37.44188,{"lat":61,"lon":60},[64,65],{"name":44,"role":45,"phone":46,"phoneExt":13,"email":47},{"name":66,"role":41,"phone":13,"phoneExt":13,"email":13},"Carolyn Rodriguez, MD, PhD",{"type":41,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"Carolyn Rodriguez","Professor","100570874",false,"NCT06712914","Rapid Non-Invasive Brain Stimulation for Hoarding Disorder","TMS-HOLA","Inclusion Criteria:\n\n1. Age 18-70 years\n2. Primary diagnosis of hoarding disorder\n3. Sufficient severity of hoarding symptoms\n4. Willing and able to understand and complete consent and study procedures\n\nExclusion Criteria:\n\n1. Psychiatric or medical conditions or medications that make participation unsafe\n2. Pregnant or nursing females\n3. Previous exposure to TMS or ECT\n4. History of any implanted device or psychosurgery","ALL","18 Years","70 Years",{"count":80,"type":81},10,"ESTIMATED","INTERVENTIONAL",[19],"This study explores whether rapid non-invasive brain stimulation can help reduce hoarding disorder symptoms.",[86,87,88],"Hoarding Disorder","Hoarding","Clutter",[90,91,92,93,94],"TMS","hoarding disorder","hoarding","clutter","iTBS","2026-04-21",{"date":97,"type":98},"2026-04-22","ACTUAL",{"date":100,"type":98},"2026-03-27",{"date":102,"type":81},"2028-01-01",{"name":5,"class":6},1]