[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100389154":3},{"organization":4,"outcomesModule":7,"designInfo":22,"detailedDescription":25,"studyPopulation":26,"armGroups":21,"interventions":27,"overallOfficials":34,"centralContacts":38,"locations":44,"responsibleParty":63,"collaborators":21,"id":65,"slug":21,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":21,"enrollmentInfo":74,"targetDuration":77,"studyType":78,"phases":21,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":46,"whyStopped":21,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"National Medical Research Center for Cardiology, Ministry of Health of Russian Federation","OTHER_GOV",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":21},[9,13],{"measure":10,"description":11,"timeFrame":12},"composite of major cardiovascular events","stroke, myocardial infarction, stent thrombosis \\[definite or probable\\], or urgent revascularization, cqrdiac death","unclusion up to 5 years",{"measure":14,"description":15,"timeFrame":12},"composite of any bleeding events","major, clinically relevant nonmajor, minor (BARC, ISTH,GARFIELD AF)",[17],{"measure":18,"description":19,"timeFrame":20},"Mutations in following genes","CYP2C9\\*, VKORC1","inclusion",null,{"allocation":21,"interventionModel":21,"interventionModelDescription":21,"primaryPurpose":21,"observationalModel":23,"timePerspective":24,"maskingInfo":21},"COHORT","PROSPECTIVE","The register is a Russian prospective single-center observational study of patients who have indications for long-term antithrombotic therapy in connection with atrial fibrillation","Hospitalized or outpatients with confirmed atrial fibrillation and CHA2DS2VASC \\> 1",[28],{"type":29,"name":30,"description":31,"armGroupLabels":21,"otherNames":32},"DRUG","Anticoagulants","oral anticoagulants, dual or triple antithrombotic theraphy",[33],"antiplatelets",[35],{"name":36,"affiliation":5,"role":37},"Elizaveta Panchenko, PhD","PRINCIPAL_INVESTIGATOR",[39],{"name":40,"role":41,"phone":42,"phoneExt":21,"email":43},"Ekaterina Kropacheva, PhD","CONTACT","+79166760695","katekrab@list.ru",[45],{"facility":5,"status":46,"city":47,"state":21,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Moscow","121552","Russia","RU",{"type":52,"coordinates":53},"Point",[54,55],37.61781,55.75204,{"lat":55,"lon":54},[58,59,61],{"name":36,"role":37,"phone":21,"phoneExt":21,"email":21},{"name":40,"role":60,"phone":21,"phoneExt":21,"email":21},"SUB_INVESTIGATOR",{"name":62,"role":60,"phone":21,"phoneExt":21,"email":21},"Oksana Zemlyanskaya, PhD",{"type":64,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100389154",false,"NCT04347187","REGistry of Long-term AnTithrombotic TherApy-2","Registry Dedicated to Assess the Risk of Ischemic and Hemorrhagic Complications of Long-term Antithrombotic Therapy in Patients With Atrial Fibrillation","REGATTA-2","Inclusion Criteria:\n\n* Documented atrial fibrillation with CHA2DS2VASC \\> 1\n\nExclusion Criteria:\n\n* Subjects who are unwilling or unable to provide informed consent. ACS within 12 months before inclusion Severe CHF (NYHA IV) Stroke within 6 months before inclusion Severe liver or muscle disease Severe kidney disease \u002F renal failure with creatinine \\> 3 mg\u002Fdl Conceivable impossibility to come in touch with the patient or his family at 1-year after the intervention","ALL","18 Years",{"count":75,"type":76},2000,"ESTIMATED","5 Years","OBSERVATIONAL","To assess the rates of ischemic and hemorrhagic complications of long-term antithrombotic therapy in patients with atrial fibrillation",[81],"Atrial Fibrillation",[83],"atrial fibrillation, coronary artery disease","2026-04-27",{"date":86,"type":87},"2026-05-01","ACTUAL",{"date":89,"type":87},"2015-01-15",{"date":91,"type":76},"2026-12-31",{"name":5,"class":6},1]