[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100369811":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":10,"centralContacts":40,"locations":50,"responsibleParty":130,"collaborators":10,"id":132,"slug":10,"hasResults":133,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":133,"sex":139,"minAge":140,"maxAge":141,"enrollmentInfo":142,"targetDuration":10,"studyType":145,"phases":10,"briefSummary":146,"conditions":147,"keywords":155,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":168},{"fullName":5,"class":6},"Associazione Italiana per lo Studio del Pancreas","OTHER",[8,14,17,21,24,27],{"label":9,"type":10,"description":10,"interventionNames":11},"Familial pancreatic cancer relatives",null,[12,13],"Radiation: MRCP","Procedure: Endoultrasonography",{"label":15,"type":10,"description":10,"interventionNames":16},"Peutz-Jeghers syndrome",[12,13],{"label":18,"type":10,"description":19,"interventionNames":20},"BRCA 1\u002F2, PALB2, p16 mutations with familiarity for PC","Known genetic mutation and at least 1 1st- or 2nd-degree relative suffering from PC",[12,13],{"label":22,"type":10,"description":10,"interventionNames":23},"Lynch syndrome with familiarity for pancreatic cancer",[12,13],{"label":25,"type":10,"description":10,"interventionNames":26},"FAMMM syndrome",[12,13],{"label":28,"type":10,"description":10,"interventionNames":29},"Hereditary and genetic pancreatitis",[12,13],[31,36],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"RADIATION","MRCP","Subjects fulfilling the \"radiological follow-up criteria\" will be submitted to MRCP or EUS according to the pancreatologist's prescription",[18,25,9,28,22,15],{"type":37,"name":38,"description":34,"armGroupLabels":39,"otherNames":10},"PROCEDURE","Endoultrasonography",[18,25,9,28,22,15],[41,46],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},"Salvatore Paiella, MD, PhD","CONTACT","00390458126009","salvatore.paiella@univr.it",{"name":47,"role":43,"phone":48,"phoneExt":10,"email":49},"Silvia Carrara, MD","+ 39 02 82247288","silvia.carrara@humanitas.it",[51,75,91,106],{"facility":52,"status":53,"city":54,"state":55,"zip":10,"country":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Istituto Clinico Humanitas","RECRUITING","Rozzano","Milan","Italy",{"type":58,"coordinates":59},"Point",[60,61],9.1559,45.38193,{"lat":61,"lon":60},[64,65,68,70,73],{"name":47,"role":43,"phone":10,"phoneExt":10,"email":49},{"name":66,"role":67,"phone":10,"phoneExt":10,"email":10},"Alessandro Zerbi, MD","PRINCIPAL_INVESTIGATOR",{"name":69,"role":67,"phone":10,"phoneExt":10,"email":10},"Luigi Laghi, MD, PhD",{"name":71,"role":72,"phone":10,"phoneExt":10,"email":10},"Laura Poliani, MD","SUB_INVESTIGATOR",{"name":74,"role":72,"phone":10,"phoneExt":10,"email":10},"Valentina Giatti",{"facility":76,"status":53,"city":77,"state":78,"zip":10,"country":56,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Ospedale Pederzoli","Peschiera del Garda","Verona",{"type":58,"coordinates":80},[81,82],10.68614,45.43912,{"lat":82,"lon":81},[85,87,89],{"name":86,"role":43,"phone":10,"phoneExt":10,"email":10},"Giovanni Butturini, MD",{"name":88,"role":72,"phone":10,"phoneExt":10,"email":10},"Alessandro Giardino, MD, PhD",{"name":90,"role":72,"phone":10,"phoneExt":10,"email":10},"Isabella Frigerio, MD, PhD",{"facility":92,"status":53,"city":55,"state":10,"zip":10,"country":56,"cosmosGeoPoint":93,"geoPoint":97,"contacts":98},"San Raffele Vita Salute University Hospital",{"type":58,"coordinates":94},[95,96],12.59836,42.78235,{"lat":96,"lon":95},[99,102,104],{"name":100,"role":43,"phone":10,"phoneExt":10,"email":101},"Massimo Falconi, MD","massimo.falconi@hsr.it",{"name":103,"role":67,"phone":10,"phoneExt":10,"email":10},"Gabriele Capurso, MD, PhD",{"name":105,"role":72,"phone":10,"phoneExt":10,"email":10},"Silvia Smaniotto",{"facility":107,"status":53,"city":78,"state":10,"zip":108,"country":56,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Chirurgia Generale e del Pancreas","37134",{"type":58,"coordinates":110},[111,112],10.9938,45.43854,{"lat":112,"lon":111},[115,116,120,121,123,125,127,128],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},{"name":117,"role":43,"phone":118,"phoneExt":10,"email":119},"Erica Secchettin, PharmD","00390458126254","erica.secchettin@univr.it",{"name":42,"role":67,"phone":10,"phoneExt":10,"email":10},{"name":122,"role":67,"phone":10,"phoneExt":10,"email":10},"Giuseppe Malleo, MD, PhD",{"name":124,"role":67,"phone":10,"phoneExt":10,"email":10},"Claudio Bassi, MD",{"name":126,"role":67,"phone":10,"phoneExt":10,"email":10},"Roberto Salvia, MD, PhD",{"name":117,"role":72,"phone":10,"phoneExt":10,"email":10},{"name":129,"role":72,"phone":10,"phoneExt":10,"email":10},"Veronica Marinelli, PhD",{"type":131,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100369811",false,"NCT04095195","Registry of Subjects at Risk of Pancreatic Cancer","Italian Registry of Families At Risk of Pancreatic Cancer","IRFARPC","Inclusion Criteria to enter the registry:\n\n* individuals with at least two relatives suffering from pancreatic cancer, with at least 1 first-degree and until the third-degree\n* subjects with known genetic mutation of BRCA2, BRCA1, p16, PALB2 with at least 1 first- or 2nd-degree relative suffering from pancreatic cancer\n* subjects suffering from FAMMM Syndrome\n* subjects suffering from Peutz-Jeghers Syndrome\n* subjects suffering from PRSS-1- or CFTR- or SPINK-1- related pancreatitis\n* subjects suffering from Lynch syndrome with at least 1 first- or 2nd-degree relative suffering from pancreatic cancer\n\nInclusion criteria to join the \"radiologic follow-up\":\n\n* 45 years or 10 years younger than the youngest index case of pancreatic cancer in the family for familial cases\n* 40 years or 5 years younger than the youngest index case of pancreatic cancer for subjects suffering from hereditary\u002Fgenetic pancreatitis, Lynch syndrome, or carrying a known BRCA 1\u002F2, PALB2, p16 genetic mutation with familiarity for pancreatic cancer\n* 30 years for subjects suffering from FAMMM, Peutz-Jeghers syndrome\n\nExclusion Criteria:\n\n\\- pregnancy","ALL","18 Years","80 Years",{"count":143,"type":144},1000,"ESTIMATED","OBSERVATIONAL","IRFARPC is a multicenter national registry designed to study the diagnosis and predisposing factors of subjects with an inherited increased risk for pancreatic cancer.",[148,149,150,151,152,153,154],"Familial Pancreatic Cancer","BRCA1 Mutation","BRCA2 Mutation","Lynch Syndrome","FAMMM - Familial Atypical Mole Malignant Melanoma Syndrome","Hereditary Pancreatitis","Peutz-Jeghers Syndrome",[148,156,151,157,158],"BRCA Mutation","Screening pancreatic cancer","Surveillance pancreatic cancer","2023-01-12",{"date":161,"type":162},"2023-01-13","ACTUAL",{"date":164,"type":162},"2019-08-20",{"date":166,"type":144},"2045-09-20",{"name":5,"class":6},4]