[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511422":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":26,"responsibleParty":43,"collaborators":10,"id":46,"slug":10,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":10,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":58,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Beijing Tiantan Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"X-ALD",null,"X-linked adrenoleukodystrophy (X-ALD) patients.",{"label":13,"type":10,"description":14,"interventionNames":10},"Carrier-control (CC)","Carriers of mutation in gene encoding ATP-binding cassette subfamily D member 1 (ABCD1), who have no X-linked adrenoleukodystrophy and are matched with the X-ALD group according to age, sex and education.",[16],{"name":17,"affiliation":18,"role":19},"Yilong Wang, MD,PhD","Beijing Tiantan Hospital, Capital Medical University, Beijing, China","PRINCIPAL_INVESTIGATOR",[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Yilong Wang, MD, PhD","CONTACT","0086-010-67092222","yilong528@aliyun.com",[27],{"facility":5,"status":28,"city":29,"state":10,"zip":30,"country":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Beijing","100050","China",{"type":33,"coordinates":34},"Point",[35,36],116.39723,39.9075,{"lat":36,"lon":35},[39,41],{"name":17,"role":23,"phone":10,"phoneExt":10,"email":40},"yilong538@gmail.com",{"name":42,"role":19,"phone":10,"phoneExt":10,"email":10},"yilong wang, M.D.",{"type":19,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"yilong Wang","Vice President of Beijing Tiantan Hospital","100511422",false,"NCT05939232","Registry of X-linked Adrenoleukodystrophy","Inclusion Criteria:\n\nX-ALD group：\n\n* Meet the diagnostic criteria of X-ALD and supported by the results of genetic and very long chain fatty acid (VLCFA) test;\n* Age: 6 - 70 years old;\n* Able to communicate normally, and complete the test of scale as instructed (confirmed by the field test of scale);\n* Sign the informed consent.\n\nCarrier-control group:\n\nHealthy people who have no significant difference in age, sex and education comparing with the X-ALD group, volunteer to participate in this study, could complete the test of scale as instructed, and meet the following criteria:\n\n* Eligible for asymptomatic carriers in genetic tests (preference of patient's mother and close relatives);\n* Age: 6 - 70 years old, able to complete the test of scale as instructed (confirmed by the field test of scale);\n* No history of psychiatric diseases.\n\nExclusion Criteria:\n\n* Other hereditary diseases;\n* Other severe central nervous diseases;\n* History of surgery of brain or eye;\n* Psychiatric and psychological diseases, such as anxiety and depression;\n* Metal foreign body or prosthesis in the human body (such as pacemaker and insulin pump), claustrophobia, and other MRI contraindications;\n* History of surgery associated with gastrointestinal tract;\n* No informed consent;\n* Unable to tolerate MRI or eye related tests.",true,"ALL","6 Years","70 Years",{"count":56,"type":57},200,"ESTIMATED","5 Years","OBSERVATIONAL","This study is a observational study conducted through recruiting X-linked adrenoleukodystrophy (X-ALD) patients, to build a comprehensive evaluation and long-term follow-up platform for X-ALD patients, and to provide a theoretical basis for the treatment and management of X-ALD patients.",[62],"X-linked Adrenoleukodystrophy",[62,64,65,66,67],"Genetic data","Phenotype","Imaging feature","Mechanism","2023-07-02",{"date":70,"type":71},"2023-07-11","ACTUAL",{"date":73,"type":57},"2023-07-20",{"date":75,"type":57},"2028-12-01",{"name":5,"class":6},1]