[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563663":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":33,"responsibleParty":57,"collaborators":59,"id":63,"slug":10,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":10,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":83,"whyStopped":10,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Hospices Civils de Lyon","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High hemolytic group",null,"Lactate Dehydrogenase Level \\> 484 IU\u002FL",[13],"Other: blood sampling",{"label":15,"type":10,"description":16,"interventionNames":17},"Low hemolytic group","Lactacte Dehydrogenase Level less or equal to 484 IU\u002FL",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"blood sampling","3 additional citrate tubes (2.7mL)",[9,15],[24,30],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},"Corine Halfon-Domenech, Dr","CONTACT","0033469166550","+33","Carine.HALFONDOMENECH@ihope.fr",{"name":31,"role":26,"phone":10,"phoneExt":10,"email":32},"Philippe CONNES, Pr","philippe.connes@univ-lyon1.fr",[34,48],{"facility":35,"status":10,"city":36,"state":10,"zip":37,"country":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Insitut Hématologique et Oncologique Pédiatrique (IHOPe)","Lyon","69008","France",{"type":40,"coordinates":41},"Point",[42,43],4.84789,45.74906,{"lat":43,"lon":42},[46],{"name":25,"role":26,"phone":47,"phoneExt":10,"email":29},"+33 4 69 16 65 50",{"facility":49,"status":10,"city":36,"state":10,"zip":37,"country":38,"cosmosGeoPoint":50,"geoPoint":52,"contacts":53},"Service de Médecine Interne - Hôpital Edouard Herriot",{"type":40,"coordinates":51},[42,43],{"lat":43,"lon":42},[54],{"name":55,"role":26,"phone":10,"phoneExt":10,"email":56},"Solène Poutrel, Dr","solene.poutrel@chu-lyon.fr",{"type":58,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[60],{"name":61,"class":62},"Laboratoire Interuniversitaire de Biologie de la Motricité (UCBL1) UR7424","UNKNOWN","100563663",false,"NCT06619093","Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood Coagulation","DREPA COAG","Inclusion Criteria:\n\n* Aged 8 years or older\n* Under clinical follow-up for a diagnosis of sickle cell disease, specifically genotypes S\u002FS, S\u002Fbeta0, or S\u002FC\n* Patient covered by a social security or equivalent health insurance plan\n* Collection of the non-opposition for adults\n* Information of the minor and collection of the non-opposition from both parents\n\nExclusion Criteria:\n\n* Patient who has undergone a transfusion or therapeutic phlebotomy within the 3 months prior to inclusion\n* Patient participating in another interventional research protocol that may interfere with the present protocol (at the investigator\\'s discretion)\n* Patient under guardianship, curatorship, or legal protection\n* Patient subject to a legal protection measure\n* Person admitted to a health or social care institution for purposes other than research","ALL","8 Years",{"count":72,"type":73},200,"ESTIMATED","OBSERVATIONAL","Sickle cell disease is characterized by chronic hemolytic anemia and blood rheological alterations. In addition, blood coagulation abnormalities have been reported in patients with sickle cell disease and hemolysis-derived products could be involved. The investigators hypothesized that patients with sickle cell disease and severe hemolysis (Lactate Dehydrogenase level \\> 484 IU\u002FL) could have an increased risk of hypercoagulable state and subsequent thromboembolic complications.",[77],"Sickle Cell Disease (SCD)",[79,80,81,82],"Hemolysis","Coagulation","Red blood cell","Sickle cell disease","NOT_YET_RECRUITING","2025-01-14",{"date":86,"type":87},"2025-01-15","ACTUAL",{"date":89,"type":73},"2025-02-01",{"date":91,"type":73},"2028-02-01",{"name":5,"class":6},2]