About this trial
The primary aim of this study is to explore the impact of a 20-minute aerobic exercise on inhibitory control, microvascular diameters, and brain function. The main questions it aims to answer are:
1. Is there a correlation among the level of physical activity, performance in inhibitory control, and the diameter of retinal microvasculature, and do retinal microcirculation parameters mediate this relationship? 2. Does short-term aerobic exercise (moderate and high intensity) improve inhibitory control and physiological markers, such as retinal diameter and frontal brain activation, compared to a sedentary control group?
Eligibility criteria
This trial accepts healthy volunteersQualifiers
right-handed (how was handedness assessed; i.e., "What hand do you write with?") with normal or corrected-to-normal vision and normal color vision
Disqualifiers
reported a history of cardiovascular, metabolic, gastrointestinal, neurological, or psychiatric disorders, medical conditions requiring medical care, substance addiction, strict diets (e.g., low- carbohydrate and Mediterranean diet), pregnancy, or lactation.
Trial design
Crossover
Treatments tested in this trial
Moderate-intensity cycling
BehavioralModerate-intensity cycling on Ergoline Ergoselect 100
Vigorous-intensity cycling
BehavioralVigorous-intensity cycling on Ergoline Ergoselect 100
Uninterrupted sitting
BehavioralUninterrupted sitting in a quiet room
Treatment groups
Trial outcomes
Primary outcomes
Cognitive function
This primary outcome measure is assessed by the modified dual-task Stroop paradigm.
Retinal Vessel Diameter
Retinal Vessel Diameter is assessed by the fully automated fundus camera.
Brain Connectivity
Brain connectivity is assessed by the NIRSport2 device
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: