Resilience Among Individuals With Opioid Use Disorder

ConditionOpioid Use Disorder

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorJohns Hopkins University

About this trial

The goal of this clinical trial is to develop a human laboratory model of resilience in people with opioid use disorder (OUD). The investigators aim to learn if objective tasks that measure cognitive, emotional, and control aspects of resilience match up with self-reported resilience during stress and non-stress situations.

Eligibility criteria

Qualifiers

Can provide informed consent and can comply with study procedures

Adults aged ≥18 years

Meet Diagnostic and Statistical Manual (DSM-5) criteria for current opioid use disorder or are currently receiving pharmacotherapy for the treatment of OUD (e.g. methadone or buprenorphine maintenance treatment [remission])

Urine sample that tests positive for opioids

Disqualifiers

Being pregnant or breastfeeding

Significant mental health or physical disorder, or life circumstances, that is judged by the investigators to interfere with study participation

Trial design

Treatments tested in this trial

Acute Stress Intervention (MAST-based)
Non-Stress Intervention (NST-based)

Treatment groups

125 Participants

are divided into 2 treatment groups

Locations

Johns Hopkins University Bayview Medical Campus21224, BaltimoreMaryland, United States

Sponsors and collaborators

Johns Hopkins University

Lead sponsor

National Institute on Drug Abuse (NIDA)

Collaborator

Source ClinicalTrials.gov