[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578052":3},{"organization":4,"outcomesModule":7,"designInfo":27,"detailedDescription":31,"studyPopulation":32,"armGroups":33,"interventions":28,"overallOfficials":28,"centralContacts":37,"locations":43,"responsibleParty":61,"collaborators":63,"id":67,"slug":28,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":28,"enrollmentInfo":76,"targetDuration":28,"studyType":79,"phases":28,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":46,"whyStopped":28,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Göteborg University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":20},[9],{"measure":10,"description":11,"timeFrame":12},"Forced vital capacity, FVC","A spirometry including FVC will be performed in the sitting position according to international guidelines.","Up to the first day after surgery",[14,17],{"measure":15,"description":16,"timeFrame":12},"Oxygen saturation","Oxygen saturation will be performed via a finger probe.",{"measure":18,"description":19,"timeFrame":12},"Forced expiratory volume during one second, FEV1","A spirometry including FEV1 will be performed in the sitting position according to international guidelines.",[21,24],{"measure":22,"description":23,"timeFrame":12},"Patient assessed overall lung function","The patients will assess their overall lung function on a study-specifik numeric rating scale from 0-10 (best)",{"measure":25,"description":26,"timeFrame":12},"Peak Expiratory Flow, PEF","A spirometry including PEF will be performed in the sitting position according to international guidelines.",{"allocation":28,"interventionModel":28,"interventionModelDescription":28,"primaryPurpose":28,"observationalModel":29,"timePerspective":30,"maskingInfo":28},null,"COHORT","PROSPECTIVE","It is well known that respiration is affected during surgery under general anesthesia. Despite optimal ventilation in a respirator during the procedure, lung volume decreases, leading to atelectasis. Other effects include increased secretions in the airways, while ciliary function deteriorates. After surgery performed under general anesthesia, the patient therefore often develops hypoventilation. This can largely be explained by lingering effects of anesthetics, reduced lung volumes, atelectasis, pain and immobilization.\n\nIn a previous study, lung effects have been studied in open and laparoscopic surgery, including after hysterectomy. With the development of robotic surgery and operations on patients with an increasing number of risk factors, complementary studies are needed.\n\nThe aim of the study is to investigate changes in lung function during robot-assisted laparoscopic surgery due to uterine cancer or endometrial intraepithelial neoplasia in the uterus, and to search for predictors of low lung volume, hypoxia and pneumonia.\n\nA consecutive series of 80 patients undergoing robot-assisted hysterectomy will be included in the study.\n\nAt the preoperative visit, a dynamic spirometry (Easyone, ndd, Medical Technologies, Switzerland) is performed in a sitting position according to international guidelines. Before the test, oxygen saturation will be measured with a finger probe. In addition, patients will assess their lung function on a visual analogue scale\n\nPostoperatively, patients will undergo the same spirometry 2-3 hours after arrival at the postoperative ward, before the first mobilization. The test will be performed while sitting in bed with the head of the bed elevated at 60˚ and with optimal pain relief (VAS\\\u003C4). Pre-test pain assessment will be recorded as well as the patient's assessment of their lung function. The day after surgery, the same test will be performed again (including assessment of pain and lung function) in the morning before and after mobilization to walk in the room. During the hospitalization, mobilization and any breathing exercises are recorded on a special protocol.","Sahlgrenska University hospital, Gothenburg, Sweden",[34],{"label":35,"type":28,"description":36,"interventionNames":28},"Study group","The study will include a consecutive series of 80 women ≥18 years of age undergoing robotic-assisted laparoscopic hysterectomy for endometrial cancer or endometrial intraepithelial neoplasia.\n\nExclusion criteria are: cognitive impairment and difficulty understanding Swedish or English instructions.",[38],{"name":39,"role":40,"phone":41,"phoneExt":28,"email":42},"Monika Fagevik Olsén, PhD","CONTACT","+46 31 342 11 95","monika.fagevik-olsen@gu.se",[44],{"facility":45,"status":46,"city":47,"state":28,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Sahlgrenska University Hospital","RECRUITING","Gothenburg","405 30","Sweden","SE",{"type":52,"coordinates":53},"Point",[54,55],11.96679,57.70716,{"lat":55,"lon":54},[58],{"name":39,"role":40,"phone":59,"phoneExt":28,"email":60},"+46 707206189","monika.fagevik-olsen@vgregion.se",{"type":62,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR",[64],{"name":65,"class":66},"Vastra Gotaland Region","OTHER_GOV","100578052",false,"NCT06806280","Respiration After Robot Assisted Laparoscopic Hysterectomy","Respiration Efter Hysterektomi Med Robotassisterad Laparoskopi- REHYR","REHYR","Inclusion Criteria:\n\n* ≥18 years of age undergoing robotic-assisted laparoscopic hysterectomy for endometrial cancer or endometrial intraepitelial neoplasty..\n\nExclusion Criteria:\n\n* cognitive impairment and difficulty understanding Swedish or English instructions.","FEMALE","18 Years",{"count":77,"type":78},80,"ESTIMATED","OBSERVATIONAL","The study will investigate how respiratory function is affected by robot-assisted surgery. Previous studies have investigated the impact after open and laparoscopic surgery, but there are no studies yet after robot-assisted surgery.\n\n80 women undergoing robot-assisted hysterectomy will undergo measurements of lung function and oxygen saturation before and after the operation.",[82],"Cancer Uterus Cervix",[84,85,86],"respiration","hysterctomy","robot assisted surgery","2025-08-20",{"date":89,"type":90},"2025-08-21","ACTUAL",{"date":92,"type":90},"2025-03-17",{"date":94,"type":78},"2026-06-30",{"name":5,"class":6},1]