[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100502079":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":29,"responsibleParty":156,"collaborators":10,"id":158,"slug":10,"hasResults":159,"nctId":160,"briefTitle":161,"officialTitle":161,"acronym":162,"eligibilityCriteria":163,"healthyVolunteers":159,"sex":164,"minAge":165,"maxAge":10,"enrollmentInfo":166,"targetDuration":10,"studyType":169,"phases":10,"briefSummary":170,"conditions":171,"keywords":10,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":177,"completionDateStruct":179,"leadSponsor":181,"locationsCount":182},{"fullName":5,"class":6},"Centre Hospitalier Annecy Genevois","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with peripheral neuropathic pain and having an indication of capsaicin patches",null,"All patients will receive as part of routine care:\n\n* Three consecutive patches of 8% capsaicin in localized application for 30 to 60 minutes once every 3 months : at M0 (study inclusion), M3 and M6, or until pain scale \\\u003C 4\u002F10 (between 0 and 10),\n* Pain assessment every 1.5 months (+\u002F-7 days), to evaluate clinical response,\n* 8% capsaicin patches if the pain assessment rises again to pain scale \\> 4\u002F10, after an initial response to treatment",[13],"Other: Questionnaires",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Questionnaires","In current practice, capsaicin patch treatment is offered to patients with a 24-hour average pain level measured by the EN numerical scale : EN scale is \\> 4 Pain monitoring questionnaires will be completed by patients every 6 weeks : Neuropathic Pain Symptom Invetory (NPSI Score), Patients' Global Impression of Change (PGIC scale), Numerical pain scale",[9],[20],{"name":21,"affiliation":5,"role":22},"Stéphane FERRANDO, Doctor","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Marion GHIDI","CONTACT","+33450637031","drci.promotion@ch-annecygenevois.fr",[30,44,58,71,84,97,110,120,133,143],{"facility":5,"status":31,"city":32,"state":10,"zip":33,"country":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"RECRUITING","Annecy","74370","France",{"type":36,"coordinates":37},"Point",[38,39],6.12565,45.90878,{"lat":39,"lon":38},[42],{"name":21,"role":26,"phone":10,"phoneExt":10,"email":43},"sferrando@ch-annecygenevois.fr",{"facility":45,"status":46,"city":47,"state":10,"zip":48,"country":34,"cosmosGeoPoint":49,"geoPoint":53,"contacts":54},"Hospices Civils de Lyon, Hôpital Pierre Wertheimer","NOT_YET_RECRUITING","Bron","69500",{"type":36,"coordinates":50},[51,52],4.91303,45.73865,{"lat":52,"lon":51},[55],{"name":56,"role":26,"phone":10,"phoneExt":10,"email":57},"Christian GOV, Doctor","Christian.gov@chu-lyon.fr",{"facility":59,"status":31,"city":60,"state":10,"zip":61,"country":34,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Centre Hospitalier Métropole Savoie","Chambéry","73000",{"type":36,"coordinates":63},[64,65],5.92079,45.56628,{"lat":65,"lon":64},[68],{"name":69,"role":26,"phone":10,"phoneExt":10,"email":70},"Valérie ROULLOT-PRADEL, Doctor","valerie.roullot.pradel@ch-metropole-savoie.fr",{"facility":72,"status":46,"city":73,"state":10,"zip":74,"country":34,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Centre Hospitalier Universitaire de Clermont-Ferrand","Clermont-Ferrand","63000",{"type":36,"coordinates":76},[77,78],3.08682,45.77969,{"lat":78,"lon":77},[81],{"name":82,"role":26,"phone":10,"phoneExt":10,"email":83},"Noémie DELAGE, Doctor","ndelage@chu-clermontferrand.fr",{"facility":85,"status":31,"city":86,"state":10,"zip":87,"country":34,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"Centre Hospitalier Universitaire Grenoble-Alpes","Grenoble","38043",{"type":36,"coordinates":89},[90,91],5.71479,45.17869,{"lat":91,"lon":90},[94],{"name":95,"role":26,"phone":10,"phoneExt":10,"email":96},"Caroline MAINDET, Doctor","cmaindet@chu-grenoble.fr",{"facility":98,"status":46,"city":99,"state":10,"zip":100,"country":34,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Hospices Civils de Lyon, Hôpital de la Croix Rousse","Lyon","69317",{"type":36,"coordinates":102},[103,104],4.84789,45.74906,{"lat":104,"lon":103},[107],{"name":108,"role":26,"phone":10,"phoneExt":10,"email":109},"Mikhail DZIADZKO, Doctor","mikhail.dziadzko@chu-lyon.fr",{"facility":111,"status":31,"city":99,"state":10,"zip":112,"country":34,"cosmosGeoPoint":113,"geoPoint":115,"contacts":116},"Centre Léon Bérard","69373",{"type":36,"coordinates":114},[103,104],{"lat":104,"lon":103},[117],{"name":118,"role":26,"phone":10,"phoneExt":10,"email":119},"Olivier RENARD, Doctor","olivier.renard@lyon.unicancer.fr",{"facility":121,"status":46,"city":122,"state":10,"zip":123,"country":34,"cosmosGeoPoint":124,"geoPoint":128,"contacts":129},"Centre Hospitalier Universitaire de Saint-Etienne","Saint-Etienne","42055",{"type":36,"coordinates":125},[126,127],4.39,45.43389,{"lat":127,"lon":126},[130],{"name":131,"role":26,"phone":10,"phoneExt":10,"email":132},"Christelle CREAC'H, Doctor","christelle.creach@univ-st-etienne.fr",{"facility":134,"status":31,"city":122,"state":10,"zip":135,"country":34,"cosmosGeoPoint":136,"geoPoint":138,"contacts":139},"Clinique Mutualiste Chirurgicale de Saint Etienne","42100",{"type":36,"coordinates":137},[126,127],{"lat":127,"lon":126},[140],{"name":141,"role":26,"phone":10,"phoneExt":10,"email":142},"Denis BAYLOT, Doctor","Denis.BAYLOT@lyon.unicancer.fr",{"facility":144,"status":46,"city":145,"state":10,"zip":146,"country":34,"cosmosGeoPoint":147,"geoPoint":151,"contacts":152},"Médipôle Lyon Villeurbanne","Villeurbanne","69100",{"type":36,"coordinates":148},[149,150],4.8795,45.76601,{"lat":150,"lon":149},[153],{"name":154,"role":26,"phone":10,"phoneExt":10,"email":155},"Mario BARMAKI, Doctor","mariobarmaki@aol.com",{"type":157,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100502079",false,"NCT05817591","Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective Cohort","CAPSICAURA","Inclusion Criteria:\n\n* Patient over 18 years of age on the day of inclusion\n* Patient who has been informed and has not expressed opposition to participating in the study,\n* Patient with peripheral neuropathic pain (whatever the etiology), defined by :\n\n  * \"Neuropathic Pain 4\" score (\"DN4\" score) ≥ 4\u002F10\n  * AND pain according to the numerical scale (EN) \\> 4\u002F10,\n  * AND stable analgesic treatment for at least 1 month,\n  * AND with or without mechanical allodynia according to the Quantitative Sensory Testing (QST) : Brush test (dynamic), Von Frey test (static)\n  * AND with or without thermal allodynia to hot or cold as determined by a ROLLTEMP-II® (Rolltemp is a device designed for quick screening of temperature sensibility over large body areas).\n* Patient responding to an indication of desensitization to high concentration capsaicin concentration and not presenting any contra-indication.\n* Patient naïve of high concentration of Capsaicin on the concerned zone\n* Patient understanding French\n\nNon-inclusion Criteria:\n\n* Patient with pain related to complex regional pain syndrome (criteria not meeting the indication for capsaicin)\n* Patient with active cancer (underlying disease and treatments may modify pain perception),\n* Patient receiving or having received in the last 3 months Botulinum toxin A on the concerned area (this treatment of neuropathic pain may modulate the effect of capsaicin and disturb the demonstration of causality),\n* Patient with planned surgery within the next 12 months on the painful site (surgery may cause neuropathic damage and\u002For bias the pain assessment),\n* Patient included in an interventional research protocol,\n* Patient under guardianship or curators,\n* Patient under legal protection\n\nExclusion Criteria:\n\nNone","ALL","18 Years",{"count":167,"type":168},400,"ESTIMATED","OBSERVATIONAL","Prospective multicenter cohort to determine patient profiles (associated factors, including allodynia) with a better response to pain desensitization by capsaicin delivered in the form of a high concentration patch (8%), in a population of patients with peripheral neuropathic pain and followed up in a pain consultation in the Auvergne Rhône Alpes region.",[172],"Peripheral Neuropathic Pain","2025-02-11",{"date":175,"type":176},"2025-02-13","ACTUAL",{"date":178,"type":176},"2023-12-14",{"date":180,"type":168},"2026-06-15",{"name":5,"class":6},10]