Results of the Use of Two Stentrievers Simultaneosly Compared With One as a Primary Treatment in Acute Ischemic Stroke

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorFundación EPIC

About this trial

Several studies have demonstrated that simultaneous treatment with two stentrievers (STs) as rescue treatment is very effective, with high recanalization rates even in this group of patients where other revascularization techniques have failed. There has been no observed increase in hemorrhagic complications. Recently, a prospective study has been published where treatment with two ST has been shown to be effective and safe if used as a first-choice treatment (not as rescue) with a successful recanalization rate (eTICI 2c/3) after the first pass of 69%. These results have been reinforced after the publication of a randomized study that confirms, in vitro, the superiority of using two ST over one.

Eligibility criteria

Qualifiers

A new disabling focal neurological deficit compatible with acute cerebral ischemia.

Any age. Informed consent obtained from the patient or representative.

NIHSS score ≥ 6.

Pre-existing functional clinical status less than or equal to 2 according to the mRS clinical scale.

Disqualifiers

Those described in the usual protocols for mechanical thrombectomy of each hospital.

Pre-existing functional clinical status greater than 2 according to the mRS clinical scale

Patients with tandem lesions of dissection or arteriosclerotic origin located in the extracranial internal carotid artery.

Initiation of treatment with a different technique than the one described.

Trial design

Treatments tested in this trial

  • Double stentriever
  • Single stentriever

Treatment groups

200 Participants
are divided into 2 treatment groups

Locations

4
Germany
Alfried Krupp Hospital Ruettenscheid Essen Germany
Spain
Hospital Universitario de Cruces48903, Barakaldo Spain
Hospital Universitario Central de Asturias33011, Oviedo Spain
Hospital Clínico Universitario de Valladolid47003, Valladolid Spain

Sponsors and collaborators

Fundación EPIC

Lead sponsor