[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638627":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":29,"locations":30,"responsibleParty":51,"collaborators":29,"id":55,"slug":29,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":29,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":29,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":29,"overallStatus":74,"whyStopped":29,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Giomer Based Sealant Without Pre Treatmen","ACTIVE_COMPARATOR","Giomer Based Sealant Without Pre Treatment With laser giomer based fissure sealnt will be applied without surface treatment",[13],"Other: phosphoric acid pretreatment",{"label":15,"type":10,"description":16,"interventionNames":17},"Giomer Based Sealant With etchant Pre Treatmen","Giomer Based Sealant Without Pre Treatment With laser giomer based fissure sealnt will be applied with phosphoric acid surface treatment",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Giomer Based Sealant With laser Pre Treatmen","Giomer Based Sealant with laser Pre Treatment giomer based fissure sealnt will be applied with laser surface treatment",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"phosphoric acid pretreatment","surface treatment with Bioactive Glass Air Abrasion giomer based fissure sealnt will be applied after surface treatment With laser",[15,19,9],[28],"laser pretreatment",null,[31,41,46],{"facility":32,"status":29,"city":33,"state":29,"zip":29,"country":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":29},"Faculty of Dentistry Cairo University","Cairo","Egypt",{"type":36,"coordinates":37},"Point",[38,39],31.24967,30.06263,{"lat":39,"lon":38},{"facility":42,"status":29,"city":33,"state":29,"zip":29,"country":34,"cosmosGeoPoint":43,"geoPoint":45,"contacts":29},"Faculty of Dentistry",{"type":36,"coordinates":44},[38,39],{"lat":39,"lon":38},{"facility":47,"status":29,"city":33,"state":29,"zip":29,"country":34,"cosmosGeoPoint":48,"geoPoint":50,"contacts":29},"Yomna",{"type":36,"coordinates":49},[38,39],{"lat":39,"lon":38},{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","yomna sayed khallaf","lecturer at faculty of dentistry Cairo university","100638627",false,"NCT07612540","Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial","Retention Rate and Caries Prevention of Giomer Based Sealant With and Without Diode Laser Pre-treatment in Young Adults: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Young adult Patients Aged 17-22.\n\n  * Good oral hygiene (plaque index score 0 or 1).\n  * Absence of abnormal occlusion habits (e.g. bruxism, nail biting, tooth clenching and mouth breathing).\n  * Patients approving to participate in the study.\n\nExclusion Criteria:\n\n* •Patients with known allergic or adverse reaction to the tested materials.\n\n  * Systematic disease that may affect participation.\n  * Xerostomic patients.",true,"ALL","17 Years","22 Years",{"count":66,"type":67},111,"ESTIMATED","INTERVENTIONAL",[70],"NA","This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years. The study compares sealant application with and without diode laser conditioning on molars with ICDAS 0-2 fissures over a 12-month follow-up period. Primary outcome is sealant retention using Simonsen's criteria, while secondary outcome is caries prevention using modified USPHS criteria. The study hypothesizes that diode laser pre-treatment may improve sealant retention and enhance caries prevention by modifying enamel surface characteristics and improving sealant penetration.",[73],"Dental Caries","NOT_YET_RECRUITING","2026-05-21",{"date":77,"type":78},"2026-05-28","ACTUAL",{"date":80,"type":67},"2026-06-01",{"date":82,"type":67},"2027-06-01",{"name":5,"class":6},3]