About this trial

Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed.

Given this limitation, we use aqueous humor (AH), the clear fluid in the front of the eye to detect specific markers, or information, that comes from the tumor itself.

Eligibility criteria

Qualifiers

All patients, age 0 days to 18 years, with a diagnosis unilateral or bilateral retinoblastoma (RB) seen at CHLA (Children's Hospital Los Angeles).

Disqualifiers

Patients referred for second opinions only and not treated at CHLA for any reason.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Locations

9
Canada
The Hospital for Sick Children (Toronto SickKids)M5G 2L3, TorontoOntario, Canada
United States
Arizona
Phoenix Children's Hospital85016, Phoenix United States
California
Children's Hospital Los Angeles90027, Los Angeles United States
Georgia
Emory University Children's Healthcare of ATL30322, Atlanta United States

Sponsors and collaborators

Children's Hospital Los Angeles

Lead sponsor

National Cancer Institute (NCI)

Collaborator