[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642736":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":29,"centralContacts":38,"locations":44,"responsibleParty":58,"collaborators":29,"id":62,"slug":29,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":29,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":29,"enrollmentInfo":70,"targetDuration":29,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":29,"overallStatus":46,"whyStopped":29,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group (A)","EXPERIMENTAL","Patients will receive the rhomboid intercostal subserratus plane block.",[13],"Other: Rhomboid intercostal subserratus plane block",{"label":15,"type":10,"description":16,"interventionNames":17},"Group (B)","Patients will receive the external oblique intercostal block.",[18],"Other: External oblique intercostal block",{"label":20,"type":21,"description":22,"interventionNames":23},"Control group","ACTIVE_COMPARATOR","Patients will not receive any interventions (IV morphine 0.1mg\u002Fkg after induction of general anesthesia).",[24],"Drug: Intravenous morphine",[26,30,33],{"type":6,"name":27,"description":11,"armGroupLabels":28,"otherNames":29},"Rhomboid intercostal subserratus plane block",[9],null,{"type":6,"name":31,"description":16,"armGroupLabels":32,"otherNames":29},"External oblique intercostal block",[15],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"DRUG","Intravenous morphine","Patients will not receive any interventions (Intravenous morphine 0.1mg\u002Fkg after induction of general anesthesia).",[20],[39],{"name":40,"role":41,"phone":42,"phoneExt":29,"email":43},"Amr R Seif, MD","CONTACT","00201066588692","amroseifo40404@gmail.com",[45],{"facility":5,"status":46,"city":47,"state":29,"zip":48,"country":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Cairo","12613","Egypt",{"type":51,"coordinates":52},"Point",[53,54],31.24967,30.06263,{"lat":54,"lon":53},[57],{"name":40,"role":41,"phone":42,"phoneExt":29,"email":43},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Amr Raafat Mahmoud Seif","Lecturer of Anesthesia, ICU and Pain Management, Faculty of Medicine, National Cancer Institute, Cairo, Egypt.","100642736",false,"NCT07642193","Rhomboid Intercostal Sub-serratus Plane Block Versus External Oblique Intercostal Block in Open Nephrectomy","Ultrasound Guided Rhomboid Intercostal Sub-serratus Plane Block Versus External Oblique Intercostal Block in Open Nephrectomy: Randomized Controlled Study","Inclusion Criteria:\n\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status II, III.\n* Body mass index (BMI): \\> 20 kg\u002F m2 and \\\u003C 35 kg\u002F m2.\n* Patients undergoing open nephrectomy.\n\nExclusion Criteria:\n\n* Patient refusal.\n* BMI \\\u003C20 kg\u002Fm2 and \\>35 kg\u002Fm2\n* Known sensitivity or contraindication to drug used in the study (local anesthetics, opioids).\n* History of psychiatric and cognitive disorders or chronic pain.\n* Contraindication to regional anesthesia e.g pre- existing peripheral neuropathies.\n* Severe respiratory or cardiac disorders.\n* Advanced liver or kidney disease.\n* Pregnancy.\n* Physical status ASA IV.\n* Coagulopathy with INR ≥ 1.6: hereditary (e.g. hemophilia, fibrinogen abnormalities \\& deficiency of factor II) - acquired (e.g. impaired liver functions with prothrombin concentration less than 60 %, vitamin K deficiency \\& therapeutic anticoagulants drugs).","ALL","18 Years",{"count":71,"type":72},90,"ESTIMATED","INTERVENTIONAL",[75],"NA","This study aims to compare time of first request of analgesia among patients undergoing rhomboid intercostal sub-serratus plane block versus external oblique intercostal block for perioperative pain management in open nephrectomy.",[78,79,80],"Rhomboid Intercostal Sub-serratus Plane Block","External Oblique Intercostal Block","Open Nephrectomy","2026-06-07",{"date":83,"type":84},"2026-06-11","ACTUAL",{"date":86,"type":84},"2026-05-02",{"date":88,"type":72},"2026-12-30",{"name":5,"class":6},1]