[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596503":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":33,"collaborators":10,"id":35,"slug":10,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":38,"acronym":10,"eligibilityCriteria":39,"healthyVolunteers":40,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":10,"studyType":47,"phases":10,"briefSummary":48,"conditions":49,"keywords":10,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":62},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Control",null,"30 control group matched as regards BMI, age and sex will be subjected to transthoracic echo and measuring serum endostatin level.",{"label":13,"type":10,"description":14,"interventionNames":10},"Cases of Psoriatic arthritis patients","30 PsA patients will be subjected to transthoracic echo, measuring serum endostatin level and modified composite psoriatic disease activity index",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Dina Maamoun ElHadba, MSc Ain Shams University","CONTACT","01006780166","DinaElhadba@med.asu.edu",[22],{"facility":5,"status":10,"city":23,"state":24,"zip":25,"country":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":10},"Cairo","Abbassia","00202","Egypt",{"type":28,"coordinates":29},"Point",[30,31],31.24967,30.06263,{"lat":31,"lon":30},{"type":34,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100596503",false,"NCT07046312","Right Ventricular Strain in Detecting Subclinical Right Ventricular Systolic Dysfunction in Psoriatic Arthritis Patients: Relation to Serum Endostatin Level","Inclusion Criteria:\n\n* Psoriatic arthritis patients according to CASPAR criteria\n* Psoriatic arthritis patients without overt cardiovascular symptoms\n* Patients with age between 20 to 50 years of age\n\nExclusion Criteria:\n\n* Other systemic autoimmune diseases\n* Patients with a history of known valvular disease, atrial fibrillation or any other arrhythmia , heart failure, ischemic cardiomyopathy severe obstructive pulmonary diseases and metabolic syndrome.\n* Patients with medical disorders as renal, congenital heart diseases, hematological disorders and cancer patients.\n* Patients taking certain drugs that have been confirmed to be risk factors for PAH such as appetite suppressant intake drugs (aminorex, fenfluramine derivatives and benfluorex) and chemotherapeutic agents.\n* Family history of myocardial infarction, cerebrovascular disease or sudden death before the age of 65y in females and 55 y in males.",true,"ALL","20 Years","50 Years",{"count":45,"type":46},60,"ESTIMATED","OBSERVATIONAL","The aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain echocardiography",[50,51],"Psoriatic Arthritis (PsA)","Subclinical Right Ventricular Systolic Dysfunction","NOT_YET_RECRUITING","2025-06-29",{"date":55,"type":56},"2025-07-01","ACTUAL",{"date":58,"type":46},"2025-07",{"date":60,"type":46},"2027-04",{"name":5,"class":6},1]