[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560775":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":35,"locations":44,"responsibleParty":61,"collaborators":63,"id":66,"slug":25,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":25,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":25,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"ETR Associates","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Yes and Know curriculum","EXPERIMENTAL","Youth will receive the Yes and Know curriculum.",[13],"Behavioral: Yes and Know curriculum",{"label":15,"type":16,"description":17,"interventionNames":18},"Nutrition Education for Adolescents","ACTIVE_COMPARATOR","Youth will receive education about adolescent nutrition.",[19],"Behavioral: Nutrition Education for Adolescents",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Yes and Know is fully virtual intervention that integrates group-based education with digital tools to support young people ages 14 to 19 by increasing their relationship and healthy life skills. The curriculum focuses on sexual and reproductive health; healthy relationships; life skills; and educational and career success. It is delivered over nine synchronous sessions of 60-minutes each for a duration of nine hours, plus asynchronous online resources and activities.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Youth will receive a fully virtual intervention that integrates group-based education with digital tools focused on adolescent nutrition and wellness. The curriculum is delivered over nine synchronous sessions of 60-minutes each for a duration of nine hours, plus asynchronous online resources and activities.",[15],[30,33],{"name":31,"affiliation":5,"role":32},"Rebecca A Braun, DrPH, MPH","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":5,"role":32},"Pamela Anderson, PhD",[36,40],{"name":31,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","510-858-0989","rebecca.braun@etr.org",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Pamela K Anderson, PhD","831-438-4060","pamela.anderson@etr.org",[45],{"facility":5,"status":46,"city":47,"state":48,"zip":49,"country":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Watsonville","California","95076","United States",{"type":52,"coordinates":53},"Point",[54,55],-121.75689,36.91023,{"lat":55,"lon":54},[58,60],{"name":59,"role":37,"phone":38,"phoneExt":25,"email":39},"Rebecca Braun, DrPH MPH",{"name":34,"role":37,"phone":42,"phoneExt":25,"email":43},{"type":62,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[64],{"name":65,"class":6},"University of California, San Francisco","100560775",false,"NCT06581536","Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth","Rigorous Evaluation of Yes and Know, a Fully Virtual Intervention Integrating Group-based Education With Digital Tools to Improve Youth Sexual Health and Well-Being","Yes and Know","Inclusion Criteria:\n\n* Ages 14-19; and\n* English speaking.\n\nExclusion Criteria:\n\n\\- Anyone not meeting inclusion criteria.","ALL","14 Years","19 Years",{"count":77,"type":78},1200,"ESTIMATED","INTERVENTIONAL",[81],"NA","This study is a 2-arm cluster randomized controlled trial with approximately 1,200 youth aged 14-19 years to assess the effectiveness of Yes and Know, a sexual health education program. To be eligible, participants must be 14-19 years old and English-speaking. Those in the treatment arm will receive Yes and Know, a synchronous virtual program delivered over multiple sessions totaling nine hours, along with asynchronous online activities and resources. Those in the control arm will receive a similarly structured program focused on nutrition education. Participants will complete brief online surveys at baseline and at 3 and 12 months after the synchronous sessions. The study will assess the program's effectiveness in reducing the prevalence of unprotected sex among youth and improving short-term outcomes, such as knowledge of reproductive health and healthy relationships, self-efficacy, and the use of reproductive health services.",[84,85,86],"Pregnancy Related","Sexually Transmitted Diseases","Adolescent Behavior","2026-05-11",{"date":89,"type":90},"2026-05-14","ACTUAL",{"date":92,"type":90},"2025-08-06",{"date":94,"type":78},"2027-12-31",{"name":5,"class":6},1]