[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557565":3},{"organization":4,"outcomesModule":7,"designInfo":21,"detailedDescription":20,"studyPopulation":24,"armGroups":20,"interventions":20,"overallOfficials":20,"centralContacts":20,"locations":25,"responsibleParty":53,"collaborators":20,"id":55,"slug":20,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":20,"eligibilityCriteria":59,"healthyVolunteers":56,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":66,"studyType":67,"phases":20,"briefSummary":68,"conditions":69,"keywords":20,"overallStatus":27,"whyStopped":20,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Zhujiang Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":20},[9],{"measure":10,"description":11,"timeFrame":12},"High resolution MRI aneurysm features","Enhancement grade was defined as follows: grade 0 for none enhancement, grade 1 for focal enhancement, involved the neck, the intermediate portion, the dome, or a bleb;grade 2 for thin annular enhancement (maximum thickness≤1 mm) , grade 3 for thick annular enhancement(maximum thickness\\>1 mm) .","1 year",[14,17],{"measure":15,"description":16,"timeFrame":12},"postoperative mRS score","MRS score definition: The MRS score, also known as the Modified Rankin Scale, is a scale used to evaluate the neurological recovery status of stroke patients. It is divided into seven levels, Level 0: completely asymptomatic. Level 1: Despite symptoms, without obvious disabilities, able to complete all frequently engaged work and activities.\n\nLevel 2: Mild disability, unable to complete all work and activities, but able to handle personal affairs without the need for assistance from others.\n\nLevel 3: Moderate disability, requiring assistance from others to walking without assistance.\n\nLevel 4: Severe disability, unable to walk without the help of others, unable to take care of one's own needs.\n\nLevel 5: Severe disability, bedridden, urinary and fecal incontinence, requiring continuous care, and requiring multiple 24-hour care from others.\n\nLevel 6: Death. The higher the mRS score, the worse the patient's prognosis.",{"measure":18,"description":19,"timeFrame":12},"postoperative aneurysm occlusion rate","Raymond classification, grade I: complete embolism; Grade II: residual aneurysm neck;",null,{"allocation":20,"interventionModel":20,"interventionModelDescription":20,"primaryPurpose":20,"observationalModel":22,"timePerspective":23,"maskingInfo":20},"COHORT","PROSPECTIVE","Inclusion Criteria:\n\n1\\. be older than 18 years of age; 2. complete a high-resolution magnetic resonance exam\n\nExclusion Criteria:\n\n1\\. aneurysm combined with other cerebrovascular diseases; 2. substandard image quality",[26,44],{"facility":5,"status":27,"city":28,"state":29,"zip":20,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Guangzhou","Guangdong","China","CN",{"type":33,"coordinates":34},"Point",[35,36],113.25,23.11667,{"lat":36,"lon":35},[39],{"name":40,"role":41,"phone":42,"phoneExt":20,"email":43},"Chuanzhi Duan","CONTACT","15536363897","doctor_duan@163.com",{"facility":45,"status":27,"city":28,"state":20,"zip":20,"country":30,"countryCode":31,"cosmosGeoPoint":46,"geoPoint":48,"contacts":49},"Southern medical university, zhujiang hospital",{"type":33,"coordinates":47},[35,36],{"lat":36,"lon":35},[50],{"name":51,"role":41,"phone":52,"phoneExt":20,"email":52},"xin feng","13681134001@163.com",{"type":54,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100557565",false,"NCT06539767","Risk Assessment and Mechanism Analysis of Intracranial Multiple Aneurysm Instability Based on High-resolution Magnetic Resonance, Imaging Histology and Hemodynamics","Inclusion Criteria:\n\n* Age 18-80 years old, male or infertile female;\n* Diagnosed as IA (intracranial aneurysm) through CTA, MRA, or DSA; And it is suitable for endovascular intervention treatment\n* The patient and\u002For their legal representative or guardian fully understand the research purpose, voluntarily participate and sign informed consent Books;\n* Patients willing to cooperate with high-resolution magnetic resonance imaging.\n* Patients willing to follow up and evaluate according to clinical research protocol requirements\n\nExclusion Criteria:\n\n* AVM (arteriovenous malformation), Moyamoya disease, or DAVF (dural arteriovenous fistula) related aneurysms;\n* Patients with contraindications for high-resolution magnetic resonance imaging;\n* Participants in clinical trials of other drugs or medical devices;\n* Patients with severe underlying diseases and extremely poor clinical conditions who cannot tolerate general anesthesia surgery;\n* Patients with poor compliance and inability to cooperate with follow-up;\n* Possible or clear history of severe allergy to contrast agents;\n* Patients with a life expectancy of less than 2 years;\n* Women who are breastfeeding and preparing for pregnancy during the study period","ALL","18 Years","80 Years",{"count":64,"type":65},1000,"ESTIMATED","2 Years","OBSERVATIONAL","This project proposes to establish a prospective cohort of MIA based on a preexisting multicenter MIA database and to combine multidimensional methods such as high-resolution magnetic resonance, hemodynamics, ambulatory blood pressure, and imaging histology to study aneurysm instability.",[70],"Arterial Aneurysm Wall Enhancement on HRMRI","2025-07-24",{"date":73,"type":74},"2025-07-28","ACTUAL",{"date":76,"type":74},"2023-01-01",{"date":78,"type":65},"2025-12-31",{"name":5,"class":6},2]