[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572093":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":41,"collaborators":10,"id":43,"slug":10,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":10,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},{"fullName":5,"class":6},"IRCCS Eugenio Medea","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Hereditary Spastic Paraplegia (HSP)",null,"Patients undergo a combined rehabilitation treatment consisting of 15 sessions on Lokomat and 15 sessions of physical therapy over three weeks for a total of 30 sessions. The same subjects undergo clinical-functional evaluations before, at the end of treatment and after a 3-month follow-up.",[13],"Device: Robot-Assisted Gait Training",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Robot-Assisted Gait Training","15 sessions of robot-assisted gait training(LOKOMAT)+ 15 session of usual treatment for a total of 30 sessions in three weeks. 45 minutes for each session.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"ELEONORA DIELLA","CONTACT","3286859456","eleonora.diella@lanostrafamiglia.it",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":10,"country":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Irccs Eugenio Medea","RECRUITING","Bosisio Parini","Italy\u002Flecco","Italy",{"type":34,"coordinates":35},"Point",[36,37],9.29,45.80075,{"lat":37,"lon":36},[40],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":42,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100572093",false,"NCT06728787","Robot-assisted Walking Treatment in Hereditary Spastic Paraplegia (HSP)","Efficacy of Robot-assisted Walking Treatment on Gait Biomechanics, Functional Outcomes, and Quality of Life in Subjects With Hereditary Spastic Paraplegia (HSP)","Inclusion Criteria:\n\n* genetic or clinical diagnosis of HSP.\n* age greater than 4 years and less than 70\n* femur length \\> 23 cm\n* ability to walk independently indoors, with or without walking aids.\n\nExclusion Criteria:\n\n* botulinum toxin injection or lower limb surgery in the previous 6 months\n* severe lower limb muscle retractions\n* severe osteoporosis\n* unhealed skin lesions in lower limbs\n* cardiovascular instability\n* acute or progressive neurological disorders\n* behavioral problemS","ALL","4 Years","70 Years",{"count":53,"type":54},50,"ESTIMATED","OBSERVATIONAL","Patients will undergo a combined rehabilitation treatment consisting of 15 sessions on Lokomat and 15 sessions of physical therapy over three weeks for a total of 30 sessions. Two sessions\u002Fday for 5 days a week. The same subjects will conduct clinical-functional assessments before, at the end of treatment, and after a 3-month follow-up:\n\n3D Gait Analysis with defined protocol (BTSBioenginner); Spastic Paraplegia Rating Scale (SPRS); Six-Minute Walk Test (6MWT), Ten Meters Walk Test (10MWT), Gross Motor Function Measure-88 (GMFM-88) and Berg Balance Scale (BBS); Quality of life questionnaires: Medical Outcome Survey Short Form (SF-36) and ad hoc questionnaire for subjective assessment of symptoms during walking (HSP-SNAP).\n\nThis study is part of normal clinical practice and does not involve any changes to the current rehabilitation course for patients.",[58],"Hereditary Spastic Paraplegia","2025-04-30",{"date":61,"type":62},"2025-05-04","ACTUAL",{"date":64,"type":62},"2012-01-01",{"date":66,"type":54},"2026-12-31",{"name":5,"class":6},1]