[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622282":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":48,"collaborators":20,"id":50,"slug":20,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":20,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":20,"enrollmentInfo":58,"targetDuration":20,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":66,"overallStatus":71,"whyStopped":20,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Postgraduate Institute of Dental Sciences Rohtak","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Oral Lichen Planus","EXPERIMENTAL","Scaling and root planing will be conducted on Oral Lichen Planus cases with gingival involvement.",[13],"Procedure: subgingival instrumentation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","subgingival instrumentation","Subgingival instrumentation like scaling and root planing of the recruited subject shall be done.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Mala Kamboj, MDS","CONTACT","+919466902477","malskam@gmail.com",[28],{"facility":29,"status":20,"city":30,"state":31,"zip":32,"country":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Post Graduate Institute of Dental Sciences","Rohtak","Haryana","124001","India",{"type":35,"coordinates":36},"Point",[37,38],76.58917,28.89447,{"lat":38,"lon":37},[41,43,46],{"name":42,"role":24,"phone":25,"phoneExt":20,"email":26},"Mala Kamboj",{"name":44,"role":45,"phone":20,"phoneExt":20,"email":20},"Ambika Gupta, MDS Oral Medicine & Radiology","SUB_INVESTIGATOR",{"name":47,"role":45,"phone":20,"phoneExt":20,"email":20},"Rajender Kumar Sharma, MDS Periodontics",{"type":49,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100622282",false,"NCT07381595","Role of Subgingival Instrumentation in Oral Lichen Planus","Impact of Subgingival Instrumentation on Clinical and Immunohistochemical Presentation of Oral Lichen Planus With Gingival Involvement","Inclusion criteria:\n\n* Clinically and histopathologically confirmed cases of OLP.\n* OLP predominantly involving the gingiva.\n* Consent obtained.\n\nExclusion criteria:\n\n* Cases which does not fulfil either clinical or histopathological criteria.\n* Unwilling to participate in the study.\n* Patients with recorded history of factors that might modify immune response (such as patient on corticosteroids or medically compromised patients or suffering from heart diseases).\n* Cases undergoing treatment of OLP within past 6 months.\n* Biopsies with inadequate or non-representative samples\n* Cases histopathologically diagnosed as Lichenoid Dysplasia or Oral Lichenoid Lesions.\n* Cases diagnosed with autoimmune disorders.","ALL","18 Years",{"count":59,"type":60},30,"ESTIMATED","INTERVENTIONAL",[63],"NA","The goal of this interventional study is to assess the clinical and histopathological changes in Oral Lichen Planus patients with gingival involvement pre and post subgingival instrumentation.\n\nObjective- Primary objective: To observe and evaluate the clinical signs and symptoms in Oral Lichen Planus with gingival involvement. Secondary objective: To observe and evaluate the Cluster of Differentiation (CD) 4+ and 8+T lymphocytes in Oral Lichen Planus with gingival involvement.\n\nStudy group: 30 cases of Oral Lichen Planus with gingival involvement",[9],[67,68,69,70],"Subgingival instrumentation","Immunohistochemistry","CD4 and CD8 lymphocytes","Clinical parameters","NOT_YET_RECRUITING","2026-02-04",{"date":74,"type":75},"2026-02-06","ACTUAL",{"date":77,"type":60},"2026-03-01",{"date":79,"type":60},"2028-12-31",{"name":5,"class":6},1]